Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma
Cancer Communications, Volume 45, Issue 5, Page 494-499, May 2025.
Jia Xiang Jin+12 more
wiley +1 more source
Understanding Functional Protein-Protein Interactions Of ABCB11 And ADA In Human And Mouse [PDF]
Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to understand Protein -Protein Interactions (PPIs) of two proteins ABCB11 and ADA from quantitative point of view ...
arxiv
HSEARCH: fast and accurate protein sequence motif search and clustering [PDF]
Protein motifs are conserved fragments occurred frequently in protein sequences. They have significant functions, such as active site of an enzyme. Search and clustering protein sequence motifs are computational intensive. Most existing methods are not fast enough to analyze large data sets for motif finding or achieve low accuracy for motif clustering.
arxiv
Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-jun [PDF]
Tobias Meyer‐ter‐Vehn+3 more
openalex +1 more source
Synovial fibroblasts: key players in rheumatoid arthritis [PDF]
Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that primarily affects the joints and ultimately leads to their destruction. The involvement of immune cells is a general hallmark of autoimmune-related disorders. In this regard,
Distler, O.+5 more
core
Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C. [PDF]
S E McDonnell+2 more
openalex +1 more source
Protein Hypernetworks: a Logic Framework for Interaction Dependencies and Perturbation Effects in Protein Networks [PDF]
Motivation: Protein interactions are fundamental building blocks of biochemical reaction systems underlying cellular functions. The complexity and functionality of such systems emerge not from the protein interactions themselves but from the dependencies between these interactions.
arxiv
Expression of the proto-oncogene c-fos and the immunolocalization of c-Fos, phosphorylated c-Fos and ERbeta proteins in the human testis [PDF]
Fabiano Conde Araujo+3 more
openalex +1 more source
Proto-oncogene c-jun expression is induced by AML1-ETO in a JNK dependent manner:possible role in the pathogenesis of acute myeloid leukemia [PDF]
Overexpression of proto-oncogene c-jun and constitutive activation of the Jun NH2-terminal kinase (JNK) signaling pathway have been implicated in the leukemic transformation process.
Elsaesser, Annika
core
Proto-Oncogene c-fos Is Transcriptionally Regulated by Parathyroid Hormone (PTH) and PTH-Related Protein in a Cyclic Adenosine Monophosphate-Dependent Manner in Osteoblastic Cells [PDF]
Laurie K. McCauley
openalex +2 more sources