Results 131 to 140 of about 106,346 (224)

Mechanisms of HRAS regulation of liver hepatocellular carcinoma for prognosis prediction. [PDF]

BMC Cancer
Fang X, Cai Y, Zhao Z, Yang S, Li Z, Peng X, Hang M, Liu P, Li Y.   +8 more
europepmc   +1 more source

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

International Journal of Cancer, EarlyView.
What's New? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini, Luciano Calzari, Gianluca Tedaldi, Michela Tebaldi, Valentina Zampiga, Ilaria Cangini, Rita Danesi, Mila Ravegnani, Valentina Arcangeli, Alessandro Passardi, Elisabetta Petracci, Sara Bravaccini, Giorgia Marisi, Alessandra Viel, Daniela Barana, Monica Pedroni, Luca Roncucci, Daniele Calistri, Davide Gentilini   +18 more
wiley   +1 more source

A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer. [PDF]

BMC Cancer
Alqahtani T, Alsubait A, Aloumi M, Alamer A, Alomari G, Alwassil OI, Obaidullah AJ, Alghamdi SS.   +7 more
europepmc   +1 more source

Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration

International Journal of Cancer, EarlyView.
What's New? SOX2 is one of the key developmental genes with a reported altered expression in many tumors. The mechanisms underlying SOX2 regulation in cancer, however, remain elusive. This study shows that TP53 transcriptionally regulates SOX2 through binding to its promoter and the SRR2 enhancer.
Patricia Lado‐Fernández, Jéssica M. Vilas, Tânia Fernandes, Carmen Carneiro, Sabela Da Silva‐Álvarez, Valentín Estévez‐Souto, Pablo Pedrosa, Miguel González‐Barcia, Luis E. Abatti, Jennifer A. Mitchell, Carmen Rivas, Gema Moreno‐Bueno, Anxo Vidal, Manuel Collado   +13 more
wiley   +1 more source

Identification of the oncogenic role of centromere protein M in non-small cell lung cancer via CDC20/MYBL2/Wnt signaling pathways. [PDF]

J Mol Histol
Wu L, Li J, Wang H, Chang X, Kong Q.
europepmc   +1 more source

Gene structure of the human receptor tyrosine kinase Ron and mutation analysis in lung cancer samples. [PDF]

, 2000
ANGELONI, DEBORA, BREATHNACH R, DANILKOVITCH A, IVANOV SI, JOHNSON BE, LEONARD EJ, LERMAN MI   +6 more
core   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

International Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai, Chunyan Luan, Zhesi Zhang, Anja Wessely, Markus V. Heppt, Carola Berking, Julio Vera   +6 more
wiley   +1 more source

Shexiang Baoxin Pills alleviate doxorubicin-induced cardiotoxicity via the reactive oxygen species-mediated AKT/Bcl-2 pathway. [PDF]

Medicine (Baltimore)
Wang S, Chen M, Qian Y, Chen X, Xu W.
europepmc   +1 more source

Soyasaponin and vertical microbial transmission: Maternal effect on the intestinal development and health of early chicks

iMeta, EarlyView.
This study investigates the vertical transmission of maternal microbiota in chickens and how it is modulated by maternal soyasaponin supplementation. Using a model spanning the reproductive tract, egg components, and developing chicks, we show that maternal gut and reproductive microbiota, including Bifidobacterium adolescentis (B.
Mingkun Gao, Shu Chen, Hao Fan, Peng Li, Aiqiao Liu, Dongli Li, Xiaomin Li, Yongfei Hu, Guofeng Han, Yuming Guo, Zengpeng Lv   +10 more
wiley   +1 more source

Branched-Chain Amino Acids Target miR-203a/fosb Axis to Promote Skeletal Muscle Growth in Common Carp (<i>Cyprinus carpio</i>). [PDF]

Aquac Nutr
Cao X, Cui H, Ji X, Lu Y, Kang Q, Lu R, Zhang Y, Xu X, Chen J.   +8 more
europepmc   +1 more source