Results 141 to 150 of about 79,488 (241)

c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells.

, 1985
Several lines of evidence suggest a role for the myc oncogene in cell proliferation. Most recently, mitogenic stimulation of quiescent lymphoid, fibroblast and epithelial cells has been demonstrated to lead to a sharp increase in c-myc RNA levels.
Eisenman, R N, Hann, S R, Thompson, C B
core  

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Pilot study: transduction of primary paraganglioma chromaffin tumour cells with inducible c-MYC drives cell proliferation. [PDF]

Exp Clin Endocrinol Diabetes
Zhang J, Rebel HG, Duesman D, Dommering CJ, Schepers A, Devilee P, Bayley JP.   +6 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Targeting SRC/STAT3 Signaling Impairs Cancer Stem Cell Activity by Downregulation of Hexokinase-2 in Radioresistant Triple-Negative Breast Cancer Cells. [PDF]

Oncol Res
Huang YH, Tu YC, Chien PJ, Lee AJ, Lin CL, Li ST, Lee YC, Chang WW.   +7 more
europepmc   +1 more source

Blockade of FGFR1 Trafficking to the Cell Surface Results in the Partial Mistargeting of the Receptor to Peroxisomes

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Fibroblast growth factor receptor 1 (FGFR1) is co‐translationally integrated into endoplasmic reticulum (ER) membranes and undergoes N‐glycosylation at several positions. This process is essential for FGFR1 progression through the secretory pathway.
Paulina Działek, Aleksandra Chorążewska, Martyna Biaduń, Jian Qiu, Natalia Porębska, Łukasz Opaliński   +5 more
wiley   +1 more source

Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review). [PDF]

Mol Med Rep
Lu J, Zhu J, Zhang L, Zheng X, Yang S, Sang Y, Yang M, Tang Y.   +7 more
europepmc   +1 more source

An immunohistochemical study of beta-catenin in HNPCC colon tumours

, 2004
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core  

Eyes Toward the Clinic: Selective Inhibition and Degradation Approaches to Bromodomain‐Containing Proteins

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley   +1 more source

Circ_0008777 promotes head and neck squamous cell carcinoma progression by elevating c-Myc expression levels via interacting with PC4 and miR-185-3p. [PDF]

Transl Oncol
Liu W, Wang Z, Li P, Liu Y, Chen J, Shi Z, Liu H, Ye J.   +7 more
europepmc   +1 more source