Results 191 to 200 of about 211,923 (331)
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene. [PDF]
Sima Lev, Yosef Yarden, David Givol
openalex +1 more source
Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian+10 more
wiley +1 more source
Characterization ofXenopus laeviscDNA clones of the c-ets-1proto-oncogene
Patrick Stiegler+9 more
openalex +2 more sources
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. [PDF]
N M van der Lugt+9 more
openalex +1 more source
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing(WGS) and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang+8 more
wiley +1 more source
The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.
HL Pahl+6 more
openalex +1 more source
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao+10 more
wiley +1 more source
5-Methylcytosine hydroxylation-mediated LINE-1 hypomethylation: a novel mechanism of proto-oncogenes activation in colorectal cancer? [PDF]
Belkhiri A, El-Rifai W.
europepmc +1 more source
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu+7 more
wiley +1 more source