Results 231 to 240 of about 191,621 (404)

Photosynthesis and calcification in the calcifying algae Halimeda discoidea studied with microsensors

, 2001
With microsensors, we measured the steady‐state microprofiles of O2, pH and Ca2+ on the topside of young segments of Halimeda discoidea, as well as the surface dynamics upon light–dark shifts. The effect of several inhibitors was studied.
de Beer, D., Larkum, A.
core  

The effect of proton-pump inhibitor therapy on disease outcomes in inflammatory bowel disease: a population-based cohort study. [PDF]

Therap Adv Gastroenterol
Deleuran T, Juul Poulsen G, Larsen L, Fallingborg J, Jepsen P, Jess T.   +5 more
europepmc   +1 more source

975 – Proton-Pump Inhibitors May Enhance Intestinal Permeability Via Dysbiosis of Gut Microbiota Under Stressed Conditions in Mice

, 2019
Shingo Takashima, Fumio Tanaka, Koji Otani, Shuhei Hosomi, Yasuaki Nagami, Koichi Taira, Noriko Kamata, Hirokazu Yamagami, Tetsuya Tanigawa, Toshio Watanabe, Yasuhiro Fujiwara   +10 more
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Proton Pump Inhibitor Use and Incident Hypertension in Menopausal Women. [PDF]

J Am Heart Assoc
Soliman AI, Wactawski-Wende J, Millen AE, Gray SL, Eaton CB, Hovey KM, Donneyong M, Saquib N, Mouton CP, Laddu D, Liu S, Shimbo D, Wassertheil-Smoller S, LaMonte MJ.   +13 more
europepmc   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Safety of Proton Pump Inhibitor in Paediatrics: A Study Based on EudraVigilance Data. [PDF]

Fundam Clin Pharmacol
Santi Laurini G, Nikitina V, Montanaro N, Motola D.   +3 more
europepmc   +1 more source

Substantive Methodological Limitations and Unexplored Causal Pathways in the Association Between Proton Pump Inhibitors and Adverse Events in Chronic Kidney Disease: A Critical Appraisal [PDF]

Shuang Wang, DuJiang Yang, Jiexiang Yang, GuoYou Wang   +3 more
openalex   +1 more source

Deprescribing versus continuation of chronic proton pump inhibitor use in adults.

Cochrane Database of Systematic Reviews, 2017
Taline Boghossian, F. Rashid, Wade Thompson, V. Welch, P. Moayyedi, C. Rojas-Fernandez, K. Pottie, B. Farrell   +7 more
semanticscholar   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source