Results 301 to 310 of about 117,687 (361)

Time to halt the overprescribing of proton pump inhibitors [PDF]

, 2016
Marks, DJB
core  

Co‐cultivation and Medium Optimization: A Strategy for Discovering Fungal‐derived Protease Inhibitors

Chemistry &Biodiversity, EarlyView.
ABSTRACT The fungi Fusarium guttiforme and Phytophthora palmivora were cultivated in four different media (Potato Dextrose Agar, Czapek, rice, and ISP2) and co‐cultured to stimulate fungal interactions and enhance secondary metabolite production. Promising extracts were fractionated, yielding compounds such as the iron complex of fusaric acid (1 ...
Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Adriano Defini Andricopulo, Gisele Barbosa, Renata Krogh, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +7 more
wiley   +1 more source

Site-specific activation of the proton pump inhibitor rabeprazole by tetrathiolate zinc centres. [PDF]

Nat Chem
Marker T, Steimbach RR, Perez-Borrajero C, Luzarowski M, Hartmann E, Schleich S, Pastor-Flores D, Espinet E, Trumpp A, Teleman AA, Gräter F, Simon B, Miller AK, Dick TP.   +13 more
europepmc   +1 more source

Tandem Mass Spectrometry and Bio‐Guided Isolation of Secondary Metabolites With Antiplasmodial Activity From Dalbergia miscolobium Bark

Chemistry &Biodiversity, EarlyView.
ABSTRACT Strategies have been employed to address antimalarial drug resistance, including the exploration of new therapeutic targets. In this study, the stem bark of Dalbergia miscolobium was investigated using in vitro assays against Plasmodium falciparum and pyruvate kinase II (PyrKII), an essential enzyme for parasite development.
Thais Bertolino Vieira Dantas, Igor M. R. Moura, Romário Pereira da Costa, Guilherme Eduardo de Souza, Richele Priscila Severino, Hélder Nagai Consolaro, Luis Felipe de Oliveira, Vinicius Bonatto, Quezia Bezerra Cass, Rafael V. C. Guido, Lorena Ramos Freitas de Sousa   +10 more
wiley   +1 more source

Gastric adenocarcinoma with submucosal invasion occurs in a sporadic fundic gland polyp of a Helicobacter pylori-uninfected patient on proton pump inhibitor. [PDF]

Clin J Gastroenterol
Kanai H, Kasuga K, Katakai S, Ishihara S, Takayama Y, Ma XH, Kosugi H, Masuo T, Takeuchi Y, Uraoka T.   +9 more
europepmc   +1 more source

Rieske Oxygenase‐Catalyzed Biotransformations in Recombinant Cupriavidus necator Fueled by Formate Oxidation

ChemBioChem, EarlyView.
In this study, formatotrophic biotransformations in recombinant Cupriavidus necator catalyzed by Rieske oxygenases (ROs) toward various oxyfunctionalized olefins are demonstrated. The oxidation of formate regenerates NADH, the ROs’ cofactor, essentially fueling the reaction.
Marleen Hallamaa, Hannah Pia Franziska Meier, Matteo Vajente, Mattia Ghirardi, Jan Deska, Sandy Schmidt   +5 more
wiley   +1 more source

Effect of Proton-Pump Inhibitor on Survival in Chinese Patients with De Novo Metastatic Hormone-Sensitive Prostate Cancer Receiving Upfront Combinatorial Docetaxel Treatment. [PDF]

Cancers (Basel)
Wong CH, Chiu JT, Ko IC, Leung DK, Siu B, Cheng CK, Lim YJ, Mok HT, Kwok CB, Tang CY, Leung SC, Liu K, Chiu PK, Teoh JY, Ng CF.   +14 more
europepmc   +1 more source

Proton Pump Inhibitor use in Hospitalized Patients: Is Overutilization Becoming a Problem?

Clinical Medicine Insights: Gastroenterology, 2012
Cheryl Durand, Kristine C. Willett, Alicia R. Desilets   +2 more
doaj  

pH Impedance Monitoring on Proton Pump Inhibitor Therapy Impacts Management Decisions in Proven GERD but not in Unproven GERD. [PDF]

Clin Gastroenterol Hepatol
Gyawali CP, Rogers BD, Yadlapati R, Roman S, Carlson DA, Pandolfino J.   +5 more
europepmc   +1 more source

Proton pump inhibitor effect on macrophage and neutrophil function: a systematic review. [PDF]

Front Immunol
Fowler JF, Eubank TA, Garey KW.
europepmc   +1 more source