Results 311 to 320 of about 185,125 (388)

The GerdQ questionnaire and high resolution manometry support the hypothesis that proton pump inhibitor‐responsive oesophageal eosinophilia is a GERD‐related phenomenon

Alimentary Pharmacology and Therapeutics, 2016
E. Savarino, S. Tolone, O. Bartolo, C. Cassan, R. Caccaro, F. Galeazzi, L. Nicoletti, R. Salvador, M. Martinato, M. Costantini, V. Savarino   +10 more
semanticscholar   +1 more source

Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network. [PDF]

Diagnostics (Basel)
Amin N, Chela H, Mubarak MF, Ayoub M, Daglilar E.   +4 more
europepmc   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

ChemMedChem, EarlyView.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

Are Children with Cystic Fibrosis Who Are Treated With a Proton-Pump Inhibitor at Risk for Vitamin B 12 Deficiency?

, 2001
Henriëtte ter Heide, Han Hendriks, Hiltje Heijmans, Paul P.C.A. Menheere, L. J. M. Spaapen, Jaap Bakker, Pierre‐Philippe Forget   +6 more
openalex   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Proton pump inhibitor use and risk of stroke: A systematic review and meta-analysis. [PDF]

Pak J Med Sci
Feng Y, Zhong Y.
europepmc   +1 more source

Molecular Fragmentation as a Strategy to Access Hyperpolarized Compounds from Para‐Hydrogen

ChemPhysChem, EarlyView.
Hyperpolarization using para‐hydrogen is a simple and cost‐effective method to dramatically increase sensitivity in magnetic resonance. When combined with chemical reactions that generate smaller fragments, a much wider array of different hyperpolarized molecules can be accessed.
Philip L. Norcott
wiley   +1 more source

Seizure and Takotsubo Cardiomyopathy Due to Proton Pump Inhibitor. [PDF]

J Community Hosp Intern Med Perspect
Acharya I, Pokharel A, Grove DA, Haas CJ.   +3 more
europepmc   +1 more source

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw, Leila‐Sophie Otten, Mart P. Kicken, Berber Piet, Bonne Biesma, Bianca van Veggel, Christi M.J. Steendam, Ben van den Borne, Lizza E.L. Hendriks, Sander Croes, Anne‐Marie C. Dingemans, Daphne W. Dumoulin, Ron H.J. Mathijssen, Jacobus A. Burgers, Alwin D.R. Huitema, Hieronymus J. Derijks, Maarten J. Deenen, Michel M. van den Heuvel, Rob ter Heine   +18 more
wiley   +1 more source

Management of uninvestigated dyspepsia: A randomized, double-blind, placebo-controlled trial of proton pump inhibitor therapy

, 2001
Linda Rabeneck, Julianne Souchek, Kimberly Wristers, Terri Menke, Naomi R. Wray, Eunice Ambriz, Iris W. Huang   +6 more
openalex   +1 more source