Results 91 to 100 of about 1,541,061 (327)

Fast, Automated, Knowledge-Based Treatment Planning for Selecting Patients for Proton Therapy Based on Normal Tissue Complication Probabilities [PDF]

, 2022
Roni Hytönen, Marije R. Vergeer, Reynald Vanderstraeten, Timo Koponen, C. Smith, Wilko F.A.R. Verbakel   +5 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Retrospective Analysis of CT-based Habitat Analysis for Predicting pCR and Survival of ESCC Treated by Neoadjuvant Chemoradiotherapy and Esophagectomy

Technology in Cancer Research & Treatment
Introduction This study sought to develop a predictive model using CT-based habitat radiomics to forecast pathological complete response (pCR) and progression-free survival (PFS) in esophageal squamous cell carcinoma (ESCC) patients receiving ...
Shujun Zhang MS, Wei-Xiang Qi MD, Feng Wang MD, Yibin Zhang MS, Jiayi Chen MD, Shengguang Zhao MD   +5 more
doaj   +1 more source

Carbon ion radiotherapy boost in the treatment of glioblastoma: a randomized phase I/III clinical trial

Cancer Communications, 2019
Background Glioblastoma (GBM) is a highly virulent tumor of the central nervous system, with a median survival 
Lin Kong, Jing Gao, Jiyi Hu, Rong Lu, Jing Yang, Xianxin Qiu, Weixu Hu, Jiade J. Lu   +7 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Parity Violation in Proton-Proton Scattering

, 1997
Measurements of parity-violating longitudinal analyzing powers (normalized asymmetries) in polarized proton-proton scattering provide a unique window on the interplay between the weak and strong interactions between and within hadrons. Several new proton-
A.A. Green, A.A. Hamian, A.M. Sekulovich, A.N. Zelenski, A.R. Berdoz, Adelberger, Bini, Bini, Birchall, C.A. Davis, C.D.P. Levy, D.C. Healey, Desplanques, Desplanques, Desplanques, Driscoll, Dubovik, Evans, Eversheim, Eversheim, Feldman, Frankfurt, G. Roy, G.M. Stinson, Goldman, Goldman, Grosnick, Haeberli, Iqbal, J. Birchall, J. Soukup, J.D. Bowman, J.R. Campbell, Kaiser, Kaiser, Kistryn, L. Lee, Lockyer, N.A. Titov, Nessi-Tedaldi, Oka, P.W. Green, P.W. Schmor, Page, R-J. Woo, R. Helmer, R. Laxdal, R.E. Mischke, S. Kadantsev, S.A. Page, S.D. Reitzner, Simonius, Simonius, Simonius, Simonius, Simonius, T. Stocki, V. Sum, W.D. Ramsay, W.T.H. van Oers, Y. Kuznetsov, Yuan   +61 more
core   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Improving total bone marrow and lymphoid irradiation: feasibility of intensity-modulated proton therapy (IMPT) and dosimetric comparison with helical tomotherapy (HT)

Radiation Oncology
Background and purpose This study aims to develop and validate a novel whole-body intensity-modulated proton therapy (IMPT) approach for total marrow/lymphatic irradiation (TMI/TMLI) and compare its efficacy to helical tomotherapy (HT).
Dayananda Shamurailatpam Sharma, Arjunan Manikandan, Gaganpreet Singh, Sanjib Gayen, Sham Sundar, Aishwarya G, Rangasamy S, Mahammood Suhail, Rajesh S, Ganapathy Krishnan, Revathi Raj, Srinivas Chilukuri, Jose Easow, Rakesh Jalali   +13 more
doaj   +1 more source

Diffraction measurements at the LHC

, 2013
Proton-proton collisions at the LHC can be classified as elastic, non-diffractive, and diffractive. In this paper we discuss various measurements of these above processes at various LHC experiments.
Csanad, M.
core  

Hydrogen molecular ions for improved determination of fundamental constants

, 2016
The possible use of high-resolution rovibrational spectroscopy of the hydrogen molecular ions H + 2 and HD + for an independent determination of several fundamental constants is analyzed.
Hilico, L, Karr, J. -Ph, Koelemeij, Jeroen, Korobov, Vladimir   +3 more
core   +3 more sources