Results 61 to 70 of about 1,453,193 (347)

Emission of neutron–proton and proton–proton pairs in neutrino scattering [PDF]

open access: yesPhysics Letters B, 2016
We use a recently developed model of relativistic meson-exchange currents to compute the neutron-proton and proton-proton yields in $( _ , ^-)$ scattering from $^{12}$C in the 2p-2h channel. We compute the response functions and cross sections with the relativistic Fermi gas model for different kinematics from intermediate to high momentum transfers.
Ruiz Simo, I.   +6 more
openaire   +5 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Gantry-based pencil beam scanning proton therapy for uveal melanoma: IMPT versus proton arc therapy

open access: yesRadiation Oncology
Background This study reports the single-institution clinical experience of multifield pencil beam scanning (PBS) intensity-modulated proton therapy (IMPT) and dosimetric comparison to proton arc for uveal melanoma (UM) in a regular PBS gantry room ...
Hang Qi   +18 more
doaj   +1 more source

Saturation of optimality limits in hadron-hadron scatterings [PDF]

open access: yes, 2003
In this paper the optimal unitarity lower bound on logarithmic slope of the diffraction peak is investigated. It is shown that the unitarity lower bound is just the optimal logarithmic slopes predicted by the principle of least distance in space of ...
Ion, D. B., Ion, M. L.
core   +3 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Statistical equilibrium and ion cyclotron absorption/emission in strongly magnetized plasmas

open access: yes, 2007
We calculate the transition rates between proton Landau levels due to non-radiative and radiative Coulomb collisions in an electron-proton plasma with strong magnetic field B.
Alexander Y. Potekhin   +67 more
core   +3 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Comparison of pencil beam and Monte Carlo calculations with ion chamber array measurements for patient-specific quality assurance

open access: yesRadiation Medicine and Protection, 2022
Objective: To determine under what conditions and criteria comparisons between calculations made with the current clinical treatment planning system (Syngo) and an in-house built TPS (TIMPS) would allow skipping of in-beam portal-specific measurements ...
Yu Deng   +7 more
doaj  

Clinical results of proton beam therapy for elderly patients with non-small cell lung cancer

open access: yesRadiation Oncology, 2018
Background The purpose of the present study was to evaluate retrospectively the efficacy and safety of proton beam therapy for elderly patients (≥80 years of age) with non-small cell lung cancer.
Takashi Ono   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy