Results 21 to 30 of about 3,306,946 (213)

Towards faster plan adaptation for proton arc therapy using initial treatment plan information [PDF]

Physics and Imaging in Radiation Oncology
Background and Purpose: Proton arc therapy (PAT) is an emerging modality delivering continuously rotating proton beams. Current PAT planning approaches are time-consuming, making them unsuitable for online adaptation.
Benjamin Roberfroid, Margerie Huet-Dastarac, Elena Borderías-Villarroel, Rodin Koffeing, John A. Lee, Ana M. Barragán-Montero, Edmond Sterpin   +6 more
doaj   +2 more sources

The proton arc therapy treatment planning problem is NP-Hard

Computers in Biology and Medicine
Proton arc therapy (PAT) is an advanced radiotherapy technique using charged particles in which the radiation device rotates continuously around the patient while irradiating the tumor. Compared to conventional, fixed-angle beam delivery mode, proton arc therapy has the potential to further improve the quality of cancer treatment by delivering accurate
Viktor Wase, Sophie Wuyckens, John A. Lee 0001, Michael Saint-Guillain   +3 more
openaire   +4 more sources

Radiation Exposure of Cardiac Conduction Nodes During Breast Proton Therapy [PDF]

International Journal of Particle Therapy, 2023
Purpose: The exposition of cardiac conduction system during breast radiation therapy has never been studied, despite the increasing use of intensity-modulated radiation therapy, which exposes larger volume to low-dose bath.
Pierre Loap, MD, Farid Goudjil, PhD, Vincent Servois, MD, Krassen Kirov, MD, Alain Fourquet, MD, Youlia Kirova, MD   +5 more
doaj   +1 more source

Proton Beam Therapy in the Treatment of Periorbital Malignancies [PDF]

International Journal of Particle Therapy, 2021
Purpose: Periorbital tumor location presents a significant challenge with 3-dimensional conformal radiation therapy or intensity modulated radiation therapy due to high tumor dose needed in the setting of close proximity to orbital structures with lower ...
Nicholas J. Damico, MD, Anna K. Wu, BS, Michael Z. Kharouta, MD, Tal Eitan, BA, Rajesh Pidikiti, PhD, Frederick B. Jesseph, MS, Mark Smith, PhD, Christian Langmack, PhD, Diana L. Mattson, CMD, Donald Dobbins, CMD, David B. Mansur, MD, Mitchell X. Machtay, MD, Jennifer A. Dorth, MD, Serah Choi, MD, PhD, Min Yao, MD, PhD, Aashish D. Bhatt, MD   +15 more
doaj   +1 more source

Normal Tissue Integral Dose as a Result of Prostate Radiation Therapy: A Quantitative Comparison Between High-Dose-Rate Brachytherapy and Modern External Beam Radiation Therapy Techniques

Advances in Radiation Oncology, 2023
Purpose: Quantification of integral radiation dose delivered during treatment for prostate cancer is lacking. We performed a comparative quantification of dose to nontarget body tissues delivered via 4 common radiation techniques: conventional volumetric
Vincent P. Grzywacz, MD, Jessica D. Arden, MD, PhD, Nikhil P. Mankuzhy, MD, Gary S. Gustafson, MD, Evelyn A. Sebastian, BS, Veronica L. Abbott, MS, Kailee J. Walters, MS, Julie A. Puzzonia, MS, Amy S. Limbacher, BS, Jason M. Hafron, MD, Daniel J. Krauss, MD   +10 more
doaj   +1 more source

A treatment planning study of proton arc therapy for para-aortic lymph node tumors: dosimetric evaluation of conventional proton therapy, proton arc therapy, and intensity modulated radiotherapy. [PDF]

Radiat Oncol, 2016
The purpose of this study is to evaluate the dosimetric benefits of a proton arc technique for treating tumors of the para-aortic lymph nodes (PALN).In nine patients, a proton arc therapy (PAT) technique was compared with intensity modulated radiation therapy (IMRT) and proton beam therapy (PBT) techniques with respect to the planning target volume ...
Rah JE, Kim GY, Oh DH, Kim TH, Kim JW, Kim DY, Park SY, Shin D.   +7 more
europepmc   +4 more sources

Dynamic Proton arc therapy for paediatric parameningeal rhabdomyosarcoma. [PDF]

J Appl Clin Med Phys
Abstract Background Parameningeal rhabdomyosarcomas (PM‐RMS) are pediatric tumors with a high risk of local failure and severe toxicity. Intensity modulated proton therapy (IMPT) offers improved healthy tissue sparing compared to conventional photon‐based radiotherapy, and proton arc therapy (PAT) might offer further improvement in healthy tissue ...
Handeland AH, Grewal HS, Boer CG, Indelicato DJ, Ytre-Hauge KS, Henjum H, Stokkevåg CH.   +6 more
europepmc   +2 more sources

Proton arc therapy reduces the dose delivered to circulating blood compared to intensity-modulated proton therapy for head-and-neck cancer. [PDF]

J Appl Clin Med Phys
Background Compared to intensity‐modulated proton therapy (IMPT), proton arc therapy (PAT) has various dosimetric advantages. However, questions have been raised over whether the larger low‐dose bath during PAT may increase radiation‐induced lymphocyte killing, which is correlated with adverse clinical outcomes.
Tattenberg S, Liu P, Cong X, Hoehr C, Ding X.   +4 more
europepmc   +2 more sources

Advancing the Role of Proton Therapy for Spine Metastases Through Diagnostic Scan–Based Planning [PDF]

International Journal of Particle Therapy, 2023
Purpose: Many patients with metastatic cancer live years beyond diagnosis, and there remains a need to improve the therapeutic ratio of metastasis-directed radiation for these patients.
Cameron W. Swanick, MD, Michael H. Shang, PhD, Kevin Erhart, PhD, Jonathan Cabrera, MS, James Burkavage, CMD, Tomas Dvorak, MD, Naren Ramakrishna, MD, PhD, Zhiqiu Li, PhD, Amish Shah, PhD, Sanford L. Meeks, Omar A. Zeidan, PhD, Patrick Kelly, MD, PhD   +11 more
doaj   +1 more source

Impact of anatomical changes on simulated proton arc therapy and intensity-modulated proton therapy for lung cancer. [PDF]

J Appl Clin Med Phys
Abstract Purpose : During lung cancer radiotherapy, inter‐fractional anatomical changes may cause the delivered dose to deviate from the primary plan, affecting tumor control and increasing the risk of normal tissue damage. This study aims to evaluate the impact of anatomical changes on the dosimetric and radiobiological performance of simulated proton
Chen W, Yang F, Zeng F, Guo H, Xu Y, Zhang T, Wu J, Zhang D, Liu G, Ding X, Wang X.   +10 more
europepmc   +2 more sources