Results 131 to 140 of about 174,170 (322)

Dynamic profiles of early biological responses to predict the treatment efficacy of proton therapy in liver cancer assessed with in vivo kinetic [18F]-FDG PET/MRI

Radiation Oncology
Background Proton beam therapy is an advanced treatment for patients with unresectable hepatocellular carcinoma. However, evaluating the response to treatment with tumor size alone is insufficient.
Yi-Hsiu Chung, I-Chun Cho, Fujie Jhang, Chi-Chang Weng, Gigin Lin, Ching-Fang Yu, Fang-Hsin Chen   +6 more
doaj   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, EarlyView.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source

Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF

Frontiers in Oncology
IntroductionTo ensure the safety and efficacy of precise proton therapy, real-time and non-intrusive monitoring of the clinical beam position is essential.
Jiqing Li, Yuexin Lu, Jiapeng Li, Jian Wang, Zhengzheng Liu, Oleg Meshkov, Jinfeng Yang, Kuanjun Fan   +7 more
doaj   +1 more source

Proton beam therapy for bone sarcomas of the skull base and spine: A retrospective nationwide multicenter study in Japan

Cancer Science, 2017
We conducted a retrospective, nationwide multicenter study to evaluate the clinical outcomes of proton beam therapy for bone sarcomas of the skull base and spine in Japan.
Y. Demizu, M. Mizumoto, T. Onoe, N. Nakamura, Y. Kikuchi, T. Shibata, T. Okimoto, H. Sakurai, T. Akimoto, K. Ono, T. Daimon, S. Murayama   +11 more
semanticscholar   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

Chemistry – A European Journal, EarlyView.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Range-compensated pencil beam scanning proton Arc therapy: a feasibility study

Communications Engineering
Proton arc therapy is a conceptual treatment technique in proton therapy that delivers a scanned proton pencil beam simultaneously as the gantry is rotated around the patient, exploiting the geometric advantages of a continuous arc with the dosimetric ...
Blake R. Smith, Ryan T. Flynn, Alonso N. Gutiérrez, Daniel E. Hyer   +3 more
doaj   +1 more source

The ‘radiation vacation’: Parents’ experiences of travelling to have their children’s brain tumours treated with proton beam therapy

Health Psychology Open, 2016
Proton beam therapy is a new form of radiotherapy. Little is known about patients’ experiences of proton beam therapy and less about parents’ experiences of children receiving treatment.
Sam G Cockle, Jane Ogden
doaj   +1 more source

Respiratory-gated Proton Beam Therapy for Intrahepatic Cholangiocarcinoma without Fiducial Markers  [PDF]

, 2023
Akihito Okubo, Sae Matsumoto, Hiroyasu Tamamura, Yoshitaka Sato, Satoko Asahi, Hitoshi Tatebe, Kazutaka Yamamoto, Keiichiro Matsushita, Makoto Sasaki, Yoshikazu Maeda, Y. Tameshige, Hajime Sunagozaka, Hiroyuki Aoyagi, Shigeyuki Takamatsu, Satoshi Kobayashi, Satoshi Shibata   +15 more
openalex   +1 more source

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, 44Sc‐Radiolabeling, and Preclinical Assessment

Chemistry – A European Journal, EarlyView.
Hypoxia‐sensitive nitroimidazole‐functionalized pyclen derivatives were successfully synthesized and radiolabeled with 44Sc(III), affording stable and inert scandium complexes. Remarkable Sc(III)‐binding capabilities of the PC2A‐mono(amide) platform enabled excellent radiolabeling performance, with ≥92–99% yields and ≥99% radiochemical purity. MicroPET
Tibor Csupász, Bayar Dahman, Tamás Gyula Gál, István Kapus, Zita Képes, Dániel Szücs, György Trencsényi, Imre Tóth, Anikó Fekete, Gyula Tircsó   +9 more
wiley   +1 more source

Linac booster for high energy proton therapy and imaging

Physical Review Accelerators and Beams, 2018
For an optimal exploitation of the benefits of proton therapy the most accurate dose delivery system should be used. The TERA Foundation has extensive experience in the field of high gradient high frequency linacs.
Alberto Degiovanni, Ugo Amaldi, Anthony J. Lomax, Jacobus M. Schippers, Lukas Stingelin, Javier Bilbao de Mendizabal   +5 more
doaj   +1 more source