Results 41 to 50 of about 189,601 (408)

Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance Anticoagulant choice and proton pump inhibitor (PPI) cotherapy could affect the risk of upper gastrointestinal tract bleeding, a frequent and potentially serious complication of oral anticoagulant treatment. Objectives To compare the incidence
W. Ray   +8 more
semanticscholar   +1 more source

Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]

open access: yes, 2019
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
core   +2 more sources

Risk of Bacterial Infection from Proton Pump Inhibitor Use

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017
Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim   +7 more
doaj   +1 more source

Efficacy of Helicobacter pylori eradication therapies: a single centre observational study

open access: yesBMC Gastroenterology, 2001
Background Many Helicobacter pylori eradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The overall results of eradication therapy in a cohort of patients are described and
Beales Ian LP
doaj   +1 more source

Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use

open access: yesJournal of Neurogastroenterology and Motility, 2018
Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for treatment of acid-related diseases including gastroesophageal reflux disease and secondary prevention of aspirin/NSAID-induced ulcers.
Y. Kinoshita, N. Ishimura, S. Ishihara
semanticscholar   +1 more source

Eradication of Helicobacter Pylori

open access: yesМедицинский совет, 2015
General idea. The article is a review of data on Helicobacter pylori resistance to antibiotics, the impact of CYP2C19 polymorphism on the metabolism of proton pump inhibitors, and recent findings on the effectiveness of eradication.
V. V. Tsukanov   +3 more
doaj   +1 more source

Proton-pump inhibitors

open access: yesSouth African Family Practice, 2015
Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is essential that clinicians understand the appropriate use of PPIs, given the significant economic ...
openaire   +4 more sources

No proton pump inhibitors? [PDF]

open access: yesBMJ, 2007
Hickson et al have tried to introduce true scientific method in an area chiefly governed by sales tactics and mass advertising, but it is good to see their admission regarding …
openaire   +2 more sources

Proton pump inhibitors overuse - consequences among patients

open access: yesJournal of Education, Health and Sport, 2019
Introduction Omeprazole was first proton pump inhibitor (PPI) approved for use by patients. Thirty years have passed since then. Due to their effectiveness, low price and safety proton pump inhibitors have become one of the most frequently prescribed ...
Patrycja Kmiotek   +2 more
doaj   +3 more sources

Clopidogrel and proton pump inhibitors [PDF]

open access: yesCanadian Medical Association Journal, 2014
The points raised by Juurlink[1][1] in response to our article[2][2] are worthy of consideration. The release kinetics of the drugs as given in the COGENT trial may have attenuated the potential for a drug–drug interaction.
openaire   +7 more sources

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