Results 41 to 50 of about 139,988 (355)
Clopidogrel and proton pump inhibitors [PDF]
Canadian Medical Association Journal, 2014 The points raised by Juurlink[1][1] in response to our article[2][2] are worthy of consideration. The release kinetics of the drugs as given in the COGENT trial may have attenuated the potential for a drug–drug interaction.
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Gut, 2000 Proton Pump Inhibitors . Edited by Olbe L. (Pp 264; illustrated; sFr198.00.) Switzerland: Birkhauser Verlag. 1999. ISBN 3 76435 897 1. The history of the development of drugs to treat the so-called acid related diseases makes a fascinating story, and the publication of this book addresses a significant chapter in that story.
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Proton Pump Inhibitors and CKD [PDF]
Journal of the American Society of Nephrology, 2016 Proton pump inhibitors (PPIs) are taken by millions of people around the world, often for many months or even years, and some take PPIs on a permanent basis. PPIs, which are available both by prescription and over the counter, generally have an excellent overall safety profile.
Mark A. Perazella, Dennis G. Moledina
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Dermatology Practical & Conceptual, 2015 Background: Sweet’s syndrome, also referred to as acute febrile neutrophilic dermatosis, can either occur as an idiopathic disorder or associated with another condition, including cancer, or induced by exposure to a drug.
Philip R. Cohen
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Pharmacology of proton pump inhibitors [PDF]
Current Gastroenterology Reports, 2008 The gastric H,K-ATPase is the primary target for the treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pK(a) of about 4.0, which allows selective accumulation in the secretory canaliculus of the parietal cell, and a benzimidazole with a second pK(a) of about ...
Jai Moo Shin, George Sachs
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Adverse Effects of Proton Pump Inhibitors—Evidence and Plausibility
International Journal of Molecular Sciences, 2019 Proton pump inhibitors (PPIs) have been increasingly used over the last decades and there are concerns about overuse and the numerous reported side-effects.
R. Fossmark, T. C. Martinsen, H. Waldum
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Proton pump inhibitors overuse - consequences among patients
Journal of Education, Health and Sport, 2019 Introduction Omeprazole was first proton pump inhibitor (PPI) approved for use by patients. Thirty years have passed since then. Due to their effectiveness, low price and safety proton pump inhibitors have become one of the most frequently prescribed ...
Patrycja Kmiotek +2 more
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Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease: A Retrospective Cohort Study
Pharmacotherapy, 2019 Proton pump inhibitors (PPIs) have been linked to acute kidney injury (AKI) and chronic kidney disease (CKD); however, current evidence has only been evaluated in a small number of studies with short follow‐up periods. This study examined the association
E. Hart +3 more
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Refractory gastroesophageal reflux disease
Arquivos de Gastroenterologia, 2012 CONTEXT: Gastroesophageal reflux disease (GERD) is a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications.
Joaquim Prado P. Moraes-Filho
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BMC Medicine, 2022 Background Approximately half of all women suffer from heartburn at some stage during pregnancy. The most effective treatment is proton pump inhibitors, but the safety of use during pregnancy cannot be guaranteed. This study aimed to elucidate the effect
Esmee M. Breddels +6 more
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