Results 141 to 150 of about 5,021,050 (358)

Possible association of dose rate and the development of late visual toxicity for patients with intracranial tumours treated with pencil beam scanned proton therapy

Radiation Oncology
Background and purpose Rare but severe toxicities of the optic apparatus have been observed after treatment of intracranial tumours with proton therapy.
Arturs Meijers, Juliane Daartz, Antje-Christin Knopf, Michelle van Heerden, Nicola Bizzocchi, Miriam Varela Vazquez, Barbara Bachtiary, Alessia Pica, Helen A Shih, Damien Charles Weber   +9 more
doaj   +1 more source

Implementation of Monte Carlo based PET verification of ion beam delivery into a TPS

Radiation Medicine and Protection, 2022
Objective: To develop and implement an ion beam teletherapy verification system based upon simulations of induced radioactivity and comparison with patient positron emission tomography (PET) scans.
Pablo Yepes, Zhuangming Shen, Michael F. Moyers, Qianxia Wang, Hongliang Chen, Jie Li, Yongqiang Li, James Lin   +7 more
doaj  

Helium-3 and Helium-4 acceleration by high power laser pulses for hadron therapy [PDF]

arXiv, 2015
The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons ...
arxiv  

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

Advanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari, Sanchyan Bhowmik, Kaiwen Zhang, Chayla L. Reeves, Danielle Vahala, Yu Suk Choi, Amy Gelmi, Alexander N. Combes, Rocky S. Tuan, Vinh X. Truong, John S. Forsythe, Jessica E. Frith   +11 more
wiley   +1 more source

The indication of palliative whole-brain radiotherapy for patients with brain metastases: a simple prognostic scoring system in the era of stereotactic radiosurgery

BMC Cancer
Background Stereotactic irradiation has become the mainstay treatment for brain metastases (BM), and whole-brain radiotherapy (WBRT) is often used for symptom palliation.
Toshiaki Hirose, Shoichi Deguchi, Kazuaki Yasui, Minoru Inoue, Tsuyoshi Onoe, Hirofumi Ogawa, Hirofumi Asakura, Koichi Mitsuya, Hideyuki Harada, Shigeyuki Murayama, Nakamasa Hayashi, Tetsuo Nishimura, Ryuta Saito   +12 more
doaj   +1 more source

Outcomes and Prognostic Factors for Locally Recurrent Rectal Cancer Treated With Proton Beam Therapy

Advances in Radiation Oncology, 2023
Purpose: Our objective was to report the outcome and prognostic factors for patients with locally recurrent rectal cancer (LRRC) treated with proton beam therapy (PBT) at our institution.
Yoshiaki Takagawa, MD, Motohisa Suzuki, MD, Hisashi Yamaguchi, MD, Ichiro Seto, MD, Yusuke Azami, MD, PhD, Masanori Machida, MD, Kanako Takayama, DDS, PhD, Takuya Tominaga, DDS, Masao Murakami, MD, PhD   +8 more
doaj  

Predicting late magnetic resonance image changes in glioma patients after proton therapy

Acta oncologica, 2019
Proton beam therapy (PBT) is expected to reduce radiation-induced side-effects compared to state-of-the-art photon treatments as the physical properties of protons offer the possibility to spare no...
J. Eulitz, E. Troost, F. Raschke, E. Schulz, B. Lutz, Almut Dutz, Steffen Löck, Patrick Wohlfahrt, Wolfgang Enghardt, C. Karpowitz, Mechthild Krause, A. Lühr   +11 more
semanticscholar   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

On the (un)effectiveness of Proton Boron Capture in Proton Therapy [PDF]

arXiv, 2018
We present calculations and simulations on the role of the p+$^{11}$B$\to$3$\alpha$ reaction in proton therapy. This reaction has been recently suggested to be responsible for a decrease in the survival probability of tumor cells, when they are irradiated with low-energy protons.
arxiv  

Dosimetric accuracy and radiobiological implications of ion computed tomography for proton therapy treatment planning

Physics in Medicine and Biology, 2019
Ion computed tomography (iCT) represents a potential replacement for x-ray CT (xCT) in ion therapy treatment planning to reduce range uncertainties, inherent in the semi-empirical conversion of xCT information into relative stopping power (RSP).
S. Meyer, F. Kamp, T. Tessonnier, A. Mairani, C. Belka, D. Carlson, C. Gianoli, K. Parodi   +7 more
semanticscholar   +1 more source