Results 101 to 110 of about 163,637 (266)

Cytosolic nucleic acid sensors and interferon beta-1 activation drive radiation-induced anti-tumour immune effects in human pancreatic cancer cells

open access: yesFrontiers in Immunology
IntroductionPancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer-related deaths worldwide with limited treatment options due to extensive radiation and chemotherapy resistance.
Sylvia Kerschbaum-Gruber   +55 more
doaj   +1 more source

2D Co‐Assembly of Solid Acids Enables Stable Superprotonic Conduction Above 260°C

open access: yesAdvanced Functional Materials, EarlyView.
A two‐dimensional co‐assembly strategy integrates antimony phosphate and phosphotungstic acid nanosheets into free‐standing inorganic lamellar membranes with confined acid–acid interfaces. The resulting interfacial hydrogen‐bond network enables anhydrous proton conductivity exceeding 0.1 S cm−1 at 260°C and supports stable high‐temperature fuel‐cell ...
Qiuning Li   +8 more
wiley   +1 more source

Balancing Hydrophobicity and Hydrophilicity: Dual Filler‐Engineered Proton Exchange Membranes for Durable, High‐Power Fuel Cells

open access: yesAdvanced Functional Materials, EarlyView.
Polarity‐matched Zr–MOFs program Nafion's nanoscale morphology during solution casting. Hydrophilic UiO‐66 preserves hydrated pathways, while hydrophobic UiO‐67 increases the proton hopping sites by densifying ionic clusters. Combining both fillers yields a membrane that delivers 176 mS cm−1 conductivity, reaches 1.46 W cm−2 under 200 kPa, and triples ...
Yonghwi Cho   +13 more
wiley   +1 more source

Comprehensive Insight into Regular Damped Oscillatory Structures from Effective Electromagnetic Form Factor Data of Some Mesons and Nucleons

open access: yesDynamics
Regular damped oscillatory structures from the “effective” electromagnetic form factors of the hadrons h=π±,K±,K0,p,n were investigated. The “effective” electromagnetic form factor behaviors were calculated from the experimental data on the total cross ...
Erik Bartoš   +4 more
doaj   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

open access: yesAdvanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro   +25 more
wiley   +1 more source

Comparative proton and photon treatment plans in children treated for neuroblastoma

open access: yesActa Oncologica
Background and purpose: Neuroblastoma is the most common extracranial solid tumour in children. Radiotherapy is commonly part of the multimodal treatment for high-risk patients.
Anna Embring   +9 more
doaj   +1 more source

Mechanical Programming of PEGDA‐β‐CD Polyrotaxane‐Based Hydrogels via Host–Guest Molecular Recognition

open access: yesAdvanced Functional Materials, EarlyView.
A mechanically programmable hydrogel for tissue engineering is developed by modulating the molecular threading density of poly(ethylene glycol) diacrylate‐β‐cyclodextrin (PEGDA‐β‐CD) polyrotaxane and combining it with β‐CD‐modified gelatin. The polyrotaxane‐guided transition from disordered pores to laminar microstructures enables precise tuning ...
Shiyi Chen   +10 more
wiley   +1 more source

Water Organization and Hydration‐Dependent Hydroxide Transport in Anion Exchange Membranes (AEM)

open access: yesAdvanced Functional Materials, EarlyView.
Hydroxide transport in anion exchange membranes is governed by the organization of water within the polymer rather than by hydration alone. A hydration‐window framework is presented to unify transport, swelling, and mechanical stability, providing guidance for designing durable membranes for fuel cells and other hydroxide‐based electrochemical ...
Phumlani F. Msomi
wiley   +1 more source

Factors Influencing the Biological Effects of FLASH Irradiation

open access: yesAntioxidants
Among the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov   +2 more
doaj   +1 more source

Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim   +28 more
wiley   +1 more source

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