Results 81 to 90 of about 534,861 (299)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Artificial intelligence unfolding for space radiation monitor data
Journal of Space Weather and Space Climate, 2018 The reliable and accurate calculation of incident particle radiation fluxes from space radiation monitor measurements, i.e. count-rates, is of great interest and importance. Radiation monitors are relatively simple and easy to implement instruments found
Aminalragia-Giamini S. +7 more
doaj +1 more source
Using the Fermilab Proton Source for a Muon to Electron Conversion Experiment [PDF]
, 2006 The Fermilab proton source is capable of providing 8 GeV protons for both the future long-baseline neutrino program (NuMI), and for a new program of low energy muon experiments.
Ankenbrandt, C. +7 more
core +2 more sources
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Molecular tipping points in plant cell surface H+ homeostasis and signalling
Quantitative Plant BiologyHydrogen, a deceptively simple element, plays crucial roles in regulating life on Earth. The concentration of hydrogen ions (H+) determines the pH of biological systems and dictates virtually all biochemical processes.
Kaltra Xhelilaj +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Ionizing Radiation Effects on Hs 578Bst Microtubules
Frontiers in Physics, 2020 Microtubules are one of the three components of the cell cytoskeleton. They are hollow wires, with a diameter of about 25 nm, formed by 13 laterally associated protofilaments composed by dimers of α and β-tubulin.
L. Bruni +8 more
doaj +1 more source
KKbar photoproduction from protons
, 2005 We study the contribution of the Drell mechanism driven by K^+ and K^- exchange to the reaction gamma N -> KKbar N. Our calculation implements the full KN and KbarN reaction amplitudes in the form of partial wave amplitudes taken from a meson-exchange ...
A. Sibirtsev +57 more
core +1 more source
On proton-proton bremsstrahlung [PDF]
Physics Letters B, 1967 Abstract The cross section for proton-proton bremsstrahlung has been calculated for soft photons in a model independent way. Comparison with experiments has been made.
openaire +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source