Reddish Colour in Cooked Ham Is Developed by a Mixture of Protoporphyrins Including Zn-Protoporphyrin and Protoporphyrin IX [PDF]
Foods, 2022 The nitrosyl–heme complex is considered the pigment responsible for the development of reddish colour in cooked hams. However, the same reddish colour was observed in a nitrite-free product elaborated with polyphenols, suggesting the presence of other ...
Claudia Giménez-Campillo +6 more
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Exceptionally selective voltage-sensor trapping of NaV1.5 channels by Mg-protoporphyrin impairs cancer cell migration [PDF]
Scientific ReportsThe human voltage-gated sodium channel hNaV1.5 is essential for cardiac excitability. Though underrecognized, NaV1.5 is also expressed in multiple cancers, promoting cell migration and malignancy.
Mahdi Jamili +7 more
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Functional analysis of bipartite NRF2 activators that overcome feedback regulation for age-related chronic diseases [PDF]
Redox BiologyActivating Nrf2 with small molecules is a promising strategy for countering aging, oxidative stress, inflammation, and various disorders, including neurodegeneration. The primary regulator of Nrf2 protein stability is Keap1, a redox sensor protein and an
Dmitry M. Hushpulian +18 more
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Matrix Selection Strategies for MALDI-TOF MS/MS Characterization of Cyclic Tetrapyrroles in Blood and Food Samples [PDF]
MoleculesCyclic tetrapyrrole derivatives such as porphyrins, chlorins, corrins (compounds with a corrin core), and phthalocyanines are a family of molecules containing four pyrrole rings usually coordinating a metal ion (Mg, Cu, Fe, Zn, etc.). Here, we report the
Mariachiara Bianco +5 more
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Erythropoietic Protoporphyria: You May Not Have Seen It, but It May Have Seen You. [PDF]
Cureus, 2022 Erythropoietic protoporphyria is a rare skin condition that commonly presents in childhood. We report a case of a 35-year-old Hispanic male with a history of sun sensitivity, presenting with complaints of immediate burning and itching of the skin on his ...
Pastore LM, Sun CW, Hsu S.
europepmc +3 more sources
Pharmaceuticals, 2022 Plasmodium has evolved to regulate the levels and oxidative states of iron protoporphyrin IX (Fe-PPIX). Antimalarial endoperoxides such as 1,2,4-trioxane artemisinin and 1,2,4-trioxolane arterolane undergo a bioreductive activation step mediated by heme (
Helenita C. Quadros +2 more
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Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease. [PDF]
PLoS ONE, 2014 High temperature requirement protein A1 (HtrA1), a secreted serine protease of the HtrA family, is associated with a multitude of human diseases. However, the exact functions of HtrA1 in these diseases remain poorly understood.
Hakryul Jo +4 more
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Chromophore-Targeting Precision Antimicrobial Phototherapy
Cells, 2023 Phototherapy, encompassing the utilization of both natural and artificial light, has emerged as a dependable and non-invasive strategy for addressing a diverse range of illnesses, diseases, and infections.
Sebastian Jusuf, Pu-Ting Dong
doaj +1 more source
International Journal of Electrochemical Science, 2020 The nitrogen-cycle is one of the most important material cycles in bioshpere. With the high nitrate concentration in ground water, it is important to find methods to reduce its content. Otherwise, it will be harmful for human healthy. The electrochemical
Jing Shen +7 more
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Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity. [PDF]
PLoS ONE, 2015 The superoxide dismutase mimetic manganese [III] tetrakis [5,10,15,20]-benzoic acid porphyrin (MnTBAP) is a potent antioxidant compound that has been shown to limit weight gain during short-term high fat feeding without preventing insulin resistance ...
Jonathan R Brestoff +9 more
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