Results 1 to 10 of about 20,002 (267)
Reddish Colour in Cooked Ham Is Developed by a Mixture of Protoporphyrins Including Zn-Protoporphyrin and Protoporphyrin IX [PDF]
Foods, 2022 The nitrosyl–heme complex is considered the pigment responsible for the development of reddish colour in cooked hams. However, the same reddish colour was observed in a nitrite-free product elaborated with polyphenols, suggesting the presence of other ...
Claudia Giménez-Campillo +6 more
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Pharmaceuticals, 2022 Plasmodium has evolved to regulate the levels and oxidative states of iron protoporphyrin IX (Fe-PPIX). Antimalarial endoperoxides such as 1,2,4-trioxane artemisinin and 1,2,4-trioxolane arterolane undergo a bioreductive activation step mediated by heme (
Helenita C. Quadros +2 more
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Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease. [PDF]
PLoS ONE, 2014 High temperature requirement protein A1 (HtrA1), a secreted serine protease of the HtrA family, is associated with a multitude of human diseases. However, the exact functions of HtrA1 in these diseases remain poorly understood.
Hakryul Jo +4 more
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Prolonged Allogeneic Islet Graft Survival by Protoporphyrins
Cell Transplantation, 2005 Transplantation of islets of Langerhans in patients with type 1 diabetes allows for improved metabolic control and insulin independence. The need for chronic immunosuppression limits this procedure to selected patients with brittle diabetes.
Antonello Pileggi +9 more
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Matrix Selection Strategies for MALDI-TOF MS/MS Characterization of Cyclic Tetrapyrroles in Blood and Food Samples [PDF]
MoleculesCyclic tetrapyrrole derivatives such as porphyrins, chlorins, corrins (compounds with a corrin core), and phthalocyanines are a family of molecules containing four pyrrole rings usually coordinating a metal ion (Mg, Cu, Fe, Zn, etc.). Here, we report the
Mariachiara Bianco +5 more
doaj +2 more sources
Acta Biochimica Polonica, 2003 Heme oxygenase-1 (HO-1), an inducible enzyme degrading heme to biliverdin, iron and carbon monoxide, is involved in regulation of inflammation and angiogenesis. Tin protoporphyrin (SnPPIX) and zinc protoporphyrin (ZnPPIX) are commonly used as competitive
Alicja Józkowicz, Józef Dulak
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Exceptionally selective voltage-sensor trapping of NaV1.5 channels by Mg-protoporphyrin impairs cancer cell migration [PDF]
Scientific ReportsThe human voltage-gated sodium channel hNaV1.5 is essential for cardiac excitability. Though underrecognized, NaV1.5 is also expressed in multiple cancers, promoting cell migration and malignancy.
Mahdi Jamili +7 more
doaj +2 more sources
Functional analysis of bipartite NRF2 activators that overcome feedback regulation for age-related chronic diseases [PDF]
Redox BiologyActivating Nrf2 with small molecules is a promising strategy for countering aging, oxidative stress, inflammation, and various disorders, including neurodegeneration. The primary regulator of Nrf2 protein stability is Keap1, a redox sensor protein and an
Dmitry M. Hushpulian +18 more
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Erythropoietic Protoporphyria: You May Not Have Seen It, but It May Have Seen You. [PDF]
Cureus, 2022 Erythropoietic protoporphyria is a rare skin condition that commonly presents in childhood. We report a case of a 35-year-old Hispanic male with a history of sun sensitivity, presenting with complaints of immediate burning and itching of the skin on his ...
Pastore LM, Sun CW, Hsu S.
europepmc +3 more sources
Erythrocyte Protoporphyrin [PDF]
Blood, 1972 Abstract Blood protoporphyrin (PROTO) concentration in man and animals has been studied as a possible means of assessing the relationship between iron supply and marrow requirements. There appear to be two fractions of PROTO: one at a level of about 30 µg/ 100 ml unrelated to either iron supply or cell age, and a second fraction that ...
E E, Langer +5 more
openaire +2 more sources