Results 31 to 40 of about 2,261 (129)

The Role of Heme Chirality in the Circular Dichroism of Heme Proteins [PDF]

, 2014
The rotational strength (R) of the Soret transition in sperm-whale myoglobin (SW Mb), the hemoglobin from Chirononms thummi thummi (C17 Hb), and human hemoglobin (hHb) has been calculated using 20 high-resolution ( R-aro > R-pep.
Pescitelli, Gennaro, Woody, Robert W.
core   +1 more source

An overview of the cutaneous porphyrias [PDF]

, 2017
This is an overview of the cutaneous porphyrias. It is a narrative review based on the published literature and my personal experience; it is not based on a formal systematic search of the literature.
A Anstey, A Anstey, A Tewari, A van Tuyll van Serooskerken, B Engin, C Landefeld, C Rimington, D Yoo, E Di Pierro, E Erlandsen, E Minder, E Minder, G Biolcati, G Elder, H Baart de la Faille, H Baart de la Faille, H Lim, H Lim, H Moseley, H Peters, I Magnus, J Bijlmer-Iest, J Bloomer, J Harms, J Langendonk, J Langendonk, J Tu, J Woolf, K Batts, K Tanigawa, L Gouya, L Gouya, L Harber, L Warren, M Boffa, M Corbett, M Ichihashi, M Mathews-Roth, M Poh-Fitzpatrick, M Sivaramakrishnan, P Aguilera, P Collins, P Farr, P Stein, P Vasconcelos, R Dawe, R Dawe, R Dawe, R Fontana, R Hift, R Katugampola, R Katugampola, R Sarkany, R Sarkany, S de Bataille, S Dover, S Dover, S Holme, S Holme, S Holme, S Schäd, S Wahlin, S Wahlin, S Wahlin, S Whatley, S Whatley, S Yamamoto, S Zaynoun, T Karamfilov, V Weimar, W Burke, Y Tokura   +71 more
core   +3 more sources

Molecular Expression and Characterization of Erythroid-Specific 5-Aminolevulinate Synthase Gain-of-Function Mutations Causing X-Linked Protoporphyria

Molecular Medicine, 2013
X-linked protoporphyria (XLP) (MIM 300752) is a recently recognized erythropoietic porphyria due to gain-of-function mutations in the erythroid-specific aminolevulinate synthase gene (ALAS2).
David F. Bishop, Vassili Tchaikovskii, Irina Nazarenko, Robert J. Desnick   +3 more
doaj   +1 more source

Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42 induced toxicity via carbon monoxide production [PDF]

, 2014
Heme oxygenase-1 (HO-1), an inducible enzyme up-regulated in Alzheimer‟s disease (AD), catabolises heme to biliverdin, Fe2+ and carbon monoxide (CO).
Al-Owais, M. M., Boyle, J. P., Dallas, Mark, Griffiths, H. H., Hettiarachchi, N. T., Hooper, N. M., Peers, C., Scragg, J. L.   +7 more
core   +1 more source

Iron Metabolism in the Disorders of Heme Biosynthesis [PDF]

, 2022
Given its remarkable property to easily switch between different oxidative states, iron is essential in countless cellular functions which involve redox reactions.
Andrea Ricci, Elena Buzzetti, Elena Corradini, Elisa Bergamini, Giada Di Betto, Paolo Ventura   +5 more
core   +1 more source

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

Pulmonary metastases of the A549-derived lung adenocarcinoma tumors growing in nude mice : a multiple case study [PDF]

, 2013
Lung adenocarcinoma is a leading human malignancy with fatal prognosis. Ninety percent of the deaths, however, are caused by metastases. The model of subcutaneous tumor xenograft in nude mice was adopted to study the growth of control and ...
Fiedor, Leszek, Jakubowska, Monika, Michalczyk-Wetula, Dominika, Podgórska, Ewa, Pyka, Janusz, Płonka, Przemysław, Susz, Anna, Urbańska, Krystyna, Śniegocka, Martyna   +8 more
core   +1 more source

Histidine-rich protein II nanoparticle delivery of heme iron load drives endothelial inflammation in cerebral malaria [PDF]

, 2023
Histidine-rich protein II (HRPII) is secreted ...
Cain, Matthew D, Du, Daniel, Goldberg, Daniel E, Klein, Robyn S, Nguyen, Suong T, Russo, Ilaria, Wu, Qingping, Wychrij, Daniel   +7 more
core   +2 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative Disease [PDF]

, 2017
Protein misfolding is implicated in numerous neurodegenerative disorders including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease.
James Shorter, Meredith E. Jackrel
core   +1 more source