Results 91 to 100 of about 47,903 (194)

Dicentrine, an Aporphine Alkaloid From Ocotea langsdorffii, Induces Mitochondrial Dysfunction and Oxidative Stress in Leishmania (L.) infantum

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Dicentrine, an aporphine alkaloid, exhibits potent in vitro antileishmanial activity against Leishmania species with high selectivity and low macrophage cytotoxicity. Mechanistic studies reveal that the compound triggers parasite death possibly by inducing mitochondrial membrane disruption and oxidative stress.
Camila S. de Freitas, Eduardo Oliveira S. da Silva, Daniela C. Tristão, Guilherme M. Antar, Daniela P. Lage, Dóris M. Abrão, Luciana M. Ribeiro Antinarelli, Elaine S. Coimbra, João Henrique G. Lago, Eduardo A. F. Coelho   +9 more
wiley   +1 more source

Murine T Cell‐Dependent Response Affects Leishmania amazonensis Amastigote Survival and Virulence

Cell Biology International, Volume 50, Issue 8, August 2026.
ABSTRACT Our group has previously described the infection course of Leishmania amazonensis in BALB/c and BALB/cnu/nu mice, which have distinct T‐cell dependent responses. In this study, lesion‐derived amastigotes exhibited differential protein expression in a host‐dependent manner.
Gustavo Henrique Corrêa Soares, Gustavo Rolim Barbosa, Beatriz Simonsen Stolf   +2 more
wiley   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

Molecular Genetics of Hepatozoon canis With a Note on Effect of Parasite on the Complete Blood Count Profile of Canine Hosts

Ecology and Evolution, Volume 16, Issue 8, August 2026.
A total of 654 blood samples were collected from healthy dogs in Punjab and Khyber Pakhtunkhwa provinces in Pakistan and screened for the presence of Hepatozoon canis. Genetic diversity of the detected H. canis DNA, infection‐associated risk factors, and changes in the complete blood count of the host due to parasitic activity were also evaluated.
Madiha Rasool, Muhammad Latif, Ioannis A. Giantsisis, Muhammad Ali, Hira Muqaddas, Muhammad Naeem, Sami Ul Haq, Gehan M. Elossaily, Esmael M. Alyami, Mona Alsolami, Ousman Brahim Mahamat, Irfan Ullah, Asmat Ullah Khan, Adil Khan, Furhan Iqbal   +14 more
wiley   +1 more source

Human salivary pH in the occurrence of human oral protozoan parasites in Ogbeke-Nike, Enugu State, Nigeria

Orapuh Journal, 2020
Introduction The interplay between human salivary potential hydrogen (pH), which measures the acidity and alkalinity level of saliva, and the prevalence of human oral protozoan parasites should be of immense interest to clinicians who are wary of the
VE ADAMU, Ndidiamaka Ijeoma Eneojo, Augustine A. Amaechi, Bertrand Ekejiuba Bright Nwoke, CMU Ajaero, Chinyere N. Ukaga   +5 more
doaj  

Environment and Host Genetics Drive Infection Outcomes in a Butterfly Host, but Do Not Interact With Each Other

Ecology and Evolution, Volume 16, Issue 8, August 2026.
This study examined how host genetics and larval food plant environment influence parasite infection outcomes in monarch butterflies (Danaus plexippus) infected with the protozoan Ophryocystis elektroscirrha. We tested for genotype × environment interactions on infection status, infection burden, lifespan, and wing size.
Ania A. Majewska, Grace Chlebove, Jacobus C. de Roode   +2 more
wiley   +1 more source

Enemy release: loss of parasites in invasive freshwater bivalves Sinanodonta woodiana and Corbicula fluminea

Ecography, Volume 2026, Issue 8, August 2026.
Invasive freshwater bivalves harm native species, ecosystems and biodiversity, and incur economic costs. The enemy release hypothesis posits that invasive species are released from enemies during the invasion process, giving them a competitive advantage in the new environment.
Binglin Deng, Nicoletta Riccardi, Pin Nie, Maria Urbańska, Timo J. Marjomäki, Wojciech Andrzejewski, Małgorzata Ożgo, Keiko Nakamura, Jouni Taskinen   +8 more
wiley   +1 more source

Seasonal Trends, Environmental Drivers, and Lessons Learned From the 2023 Cholera Outbreak in Chattogram, Bangladesh: A Descriptive Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Acute watery diarrhea (AWD) remains a major global public health problem, and cholera continues to cause substantial morbidity and mortality in settings with inadequate water, sanitation, and hygiene (WASH). Chattogram, a coastal district of Bangladesh, is particularly vulnerable due to seasonal hydroclimatic changes ...
Immamul Muntasir, Md. Jahidur Rahman, Sayik Bin Alam, Abir Shaqran Mahmood, Tanvir Ahmed, Mithun Bahadur, Farzana Islam Khan, Kyaw Thowai Prue Prince, Mohammad Rashedul Hassan, Zakir Hossain Habib, Tahmina Shirin   +10 more
wiley   +1 more source

Mitochondrial Genome Reduction and Accelerated Evolution in Planktonic Foraminiferans

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
The mitochondrial genomes of the eukaryotic lineage Retaria (Foraminifera and Radiolaria) show reductions in multiple gene categories, including complex I, transfer RNAs (tRNAs), ribosomal proteins, and ribosomal RNAs. In planktonic foraminifera, this reduction is even more pronounced, with the potential loss of atp and other genes.
Hsin‐Tung Lai, Ming‐Wei Lai, Tzu‐Haw Wang, Haojia Ren, Chuan Ku   +4 more
wiley   +1 more source

Lower Respiratory Microbiome Dysbiosis Is Associated With Poor Prognosis in Acute Severe Lower Respiratory Tract Infection

MedComm, Volume 7, Issue 8, August 2026.
Acute severe lower respiratory tract infection (asLRTI) present lower alpha‐diversity in lower respiratory tract microbiome (LRTM). Five clusters (C1–C5) were grouped, and cluster C3 was strongly associated with poor prognosis and reduced survival.
Minghua Zhan, Hongbin Chen, Ziyao Li, Si Liu, Binghuai Lu, Zhang Wang, Hui Wang   +6 more
wiley   +1 more source