T cell receptor Vβ staining identifies the malignant clone in adult T cell leukemia and reveals killing of leukemia cells by autologous CD8+ T cells [PDF]
, 2016 There is growing evidence that CD8+ cytotoxic T lymphocyte (CTL) responses can contribute to long-term remission of many malignancies. The etiological agent of adult T-cell leukemia/lymphoma (ATL), human T lymphotropic virus type-1 (HTLV-1), contains ...
Bangham, CRM +7 more
core +5 more sources
In-vivo mutation rates and fitness landscape of HIV-1
, 2016 Mutation rates and fitness costs of deleterious mutations are difficult to measure in vivo but essential for a quantitative understanding of evolution. Using whole genome deep sequencing data from longitudinal samples during untreated HIV-1 infection, we
Albert, Jan +4 more
core +1 more source
Longitudinal sequencing of HIV-1 infected patients with low-level viremia for years while on ART shows no indications for genetic evolution of the virus [PDF]
, 2017 HIV-infected patients on antiretroviral therapy (ART) may present low-level viremia (LLV) above the detection level of current viral load assays.
Dauwe, Kenny +7 more
core +1 more source
Brazilian Journal of Medical and Biological Research, 2009 Salvador (BA, Brazil) is an endemic area for human T-cell lymphotrophic virus type 1 (HTLV-1). The overall prevalence of HTLV-1 infection in the general population has been estimated to be 1.76%.
J. Primo +6 more
doaj
BLV-CoCoMo-qPCR: a useful tool for evaluating bovine leukemia virus infection status
BMC Veterinary Research, 2012 Background Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide, imposing a severe economic impact on the dairy cattle industry.
Jimba Mayuko +8 more
doaj +1 more source
A novel association of BoLA DRB3 alleles in BLV infected cattle with different proviral loads
Brazilian Journal of Veterinary Research and Animal Science, 2017 O vírus da leucemia bovina (BLV) está associado à doença neoplásica mais comum do gado bovino. O BLV tem uma disseminação silenciosa no rebanho devido à troca de células infectadas, assim, a concentração de células BLV infectadas no sangue deve desempenhar um papel importante no sucesso da transmissão viral.
Nieto Farías, María Victoria +6 more
openaire +4 more sources
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
Veterinary Research, 2012 Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) expression (transcript levels ...
Crespo Helena +9 more
doaj +1 more source
Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes. [PDF]
, 2003 CD8+ class I-restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed.
Ali, Ayub +6 more
core
BoLA-DRB3 Polymorphism Associated with Bovine Leukemia Virus Infection and Proviral Load in Holstein Cattle in Egypt. [PDF]
Pathogens, 2023 Hamada R +8 more
europepmc +1 more source
Low proviral load in the Kumamoto strain of Japanese Brown cattle infected with the bovine leukemia virus. [PDF]
BMC Vet Res, 2023 Inenaga T +7 more
europepmc +1 more source