Results 91 to 100 of about 18,625 (239)

A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter. [PDF]

open access: yes, 2017
The principal barrier to the eradication of HIV/AIDS is the existence of latent viral reservoirs. One strategy to overcome this barrier is to use latency-reversing agents (LRAs) to reactivate the latent proviruses, which can then be eliminated by ...
Ao, Ming-Tao   +9 more
core   +2 more sources

Investigation of the Seroprevalence of Lentivirus ovivismae and Lentivirus capartenc (Formerly Known as Maedi‐Visna and Caprine Arthritis‐Encephalitis Virus) Infections in Sheep and Goats in the Yozgat Region

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study conducted in the Yozgat region determined a prevalence of 6.35% for maedi‐visna in sheep and 17.5% for caprine arthritis encephalitis in goats, providing critical data for small ruminant health and disease management in the area. ABSTRACT Background Lentivirus ovivismae and Lentivirus capartenc (formerly maedi‐visna and caprine arthritis ...
Emre Sayar   +3 more
wiley   +1 more source

Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA [PDF]

open access: yes, 2017
From the 13th to 16th February 2017, researchers from around the world convened for the 24th annual Conference on Retroviruses and Opportunistic Infections (CROI) at the Washington State Convention Center in Seattle, Washington.
Bhagani, Sanjay   +12 more
core   +5 more sources

Decoding HIV‐1 Next Move Through Matrix Protein p17 Quasi‐Species

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
HIV‐1 mutants expressing clonogenic HIV‐1 matrix protein p17 variants (vp17s) are spreading, increasing their prevalence worldwide. In RNA viruses, quasi‐species are transmitted among hosts, leading to the generation of new master sequences. We developed a next‐generation sequence approach to evaluate the frequency of vp17 quasi‐species in people ...
Serena Messali   +7 more
wiley   +1 more source

G-Quadruplex DNA and Other Non-Canonical B-Form DNA Motifs Influence Productive and Latent HIV-1 Integration and Reactivation Potential

open access: yesViruses, 2022
The integration of the HIV-1 genome into the host genome is an essential step in the life cycle of the virus and it plays a critical role in the expression, long-term persistence, and reactivation of HIV expression. To better understand the local genomic
Hannah O. Ajoge   +9 more
doaj   +1 more source

The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]

open access: yes, 2013
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis   +95 more
core   +3 more sources

The Importance of Pediatric Nonhuman Primate Models in Translational HIV Research

open access: yesJournal of Medical Primatology, Volume 55, Issue 2, April 2026.
ABSTRACT Despite extraordinary global progress in the prevention and treatment of HIV, pediatric HIV remains a significant and under‐addressed component of the global epidemic. In her keynote presentation at the Pediatric Nonhuman Primate (NHP) Workshop in October 2024, Dr.
Ann Chahroudi
wiley   +1 more source

Feline blood donation via cephalic intravenous catheter: A novel method

open access: yesVeterinary Record, Volume 198, Issue 6, Page e263-e265, 14/21 March 2026.
Abstract Background Feline jugular blood donation requires heavy sedation or a very compliant cat. Donation using an intravenous catheter requires less restraint and potentially decreases stress. Methods This was an observational study of feline blood donors at a veterinary hospital between February and June 2023.
Charlotte Russo, Karen Humm
wiley   +1 more source

Barriers to infection of human cells by feline leukemia virus: insights into resistance to zoonosis [PDF]

open access: yes, 2017
The human genome displays a rich fossil record of past gamma-retrovirus infections, yet no current epidemic is evident, despite environmental exposure to viruses that infect human cells in vitro.
Ahmad, Shamim   +9 more
core   +1 more source

Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy

open access: yesViruses, 2023
HIV establishes a persistent viral reservoir in the brain despite viral suppression in blood to undetectable levels on antiretroviral therapy (ART). The brain viral reservoir in virally suppressed HIV+ individuals is not well-characterized. In this study,
Dana Gabuzda   +4 more
doaj   +1 more source

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