Results 111 to 120 of about 13,226 (233)

Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

Nature Communications, 2017
Human T-cell leukaemia virus type-1 (HTLV-1) and bovine leukaemia virus (BLV) infect T- and B-lymphocytes, respectively, provoking a polyclonal expansion that will evolve into an aggressive monoclonal leukaemia in ∼5% of individuals following a ...
N. Rosewick, K. Durkin, M. Artesi, A. Marçais, V. Hahaut, P. Griebel, N. Arsic, V. Avettand-Fenoel, A. Burny, C. Charlier, O. Hermine, M. Georges, A. Van den Broeke   +12 more
semanticscholar   +1 more source

Chromosomal localization of Emv-16 and Emv-17, two closely linked ecotropic proviruses of RF/J mice [PDF]

, 1986
Arthur M. Buchberg, Benjamin A. Taylor, N.A. Jenkins, N G Copeland   +3 more
openalex   +1 more source

Measuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintained

Retrovirology, 2018
The identification of the most appropriate marker to measure reservoir size has been a great challenge for the HIV field. Quantitative viral outgrowth assay (QVOA), the reference standard to quantify the amount of replication-competent virus, has several
Marilia Rita Pinzone, Una O’Doherty
doaj   +1 more source

Molecular cloning and characterization of mouse mammary tumor proviruses from a T-cell lymphoma [PDF]

, 1986
Jaquelin P. Dudley, Ann Arfsten, Chih-Li Lilian Hsu, Christine A. Kozak, R Risser   +4 more
openalex   +1 more source

The role of integration and clonal expansion in HIV infection: live long and prosper

Retrovirology, 2018
Integration of viral DNA into the host genome is a central event in the replication cycle and the pathogenesis of retroviruses, including HIV. Although most cells infected with HIV are rapidly eliminated in vivo, HIV also infects long-lived cells that ...
Elizabeth M. Anderson, Frank Maldarelli
doaj   +1 more source

Somatically acquired recombinant murine leukemia proviruses in thymic leukemias of AKR/J mice [PDF]

, 1983
Winship Herr, W Gilbert
openalex   +1 more source

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion

Mobile DNA, 2017
BackgroundAbout half of the human genome is constituted of transposable elements, including human endogenous retroviruses (HERV). HERV sequences represent the 8% of our genetic material, deriving from exogenous infections occurred millions of years ago ...
Nicole Grandi, M. Cadeddu, Maria Paola Pisano, F. Esposito, J. Blomberg, E. Tramontano   +5 more
semanticscholar   +1 more source

Reactivation of HIV-1 proviruses in immune-compromised mice engrafted with human VOA-negative CD4+ T cells

Journal of Virus Eradication, 2017
Background: HIV-1 infection remains incurable on antiretroviral therapy (ART) due to virus latency. To date, enhanced co-culture assays, including viral outgrowth assays (VOA), are commonly used to measure HIV-1 latent reservoirs and evaluate latency ...
Zhe Yuan, Guobin Kang, Wuxun Lu, Qingsheng Li   +3 more
doaj   +1 more source

Reviewer #1 (Public Review): Persistence of intact HIV-1 proviruses in the brain during suppressive antiretroviral therapy

, 2023
Weiwei Sun, Rassadkina Yelizaveta, Ce Gao, Collens Sarah Isabel, Lian Xiaodong, Solomon Isaac H., Mukerji Shibani, Yu Xu G., Lichterfeld Mathias   +8 more
openalex   +1 more source

Intact proviruses are enriched in the colon and associated with PD-1+TIGIT− mucosal CD4+ T cells of people with HIV-1 on antiretroviral therapyResearch in context

EBioMedicine
Summary: Background: The persistence of intact replication-competent HIV-1 proviruses is responsible for the virological rebound off treatment. The gut could be a major reservoir of HIV-1 due to the high number of infected target cells.
Camille Vellas, Manon Nayrac, Nived Collercandy, Mary Requena, Nicolas Jeanne, Justine Latour, Chloé Dimeglio, Michelle Cazabat, Karl Barange, Laurent Alric, Nicolas Carrere, Guillaume Martin-Blondel, Jacques Izopet, Pierre Delobel   +13 more
doaj   +1 more source