Results 131 to 140 of about 18,625 (239)

Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas

Advanced Science, Volume 13, Issue 1, 5 January 2026.
To the best of the knowledge, this study provides the largest viral genome dataset from a continental shelf sea. It reveals that over half of vOTUs are novel, highlighting the remarkable viral novelty in the eastern continental shelf seas of China (ECSSC).
Xiaoyue Guo, Yantao Liang, Chen Gao, Hao Yu, Meiwen Wang, Hongbing Shao, Yeqing Yang, David Paez‐Espino, Andrew McMinn, Min Wang   +9 more
wiley   +1 more source

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

Nature Microbiology, 2018
Host factors that silence provirus transcription in CD4+ memory T cells help HIV-1 escape eradication by the host immune system and by antiviral drugs1. These same factors, however, must be overcome for HIV-1 to propagate.
L. Yurkovetskiy, M. H. Guney, Kyusik Q Kim, Shih Lin Goh, S. McCauley, Ann Dauphin, W. Diehl, Jeremy Luban   +7 more
semanticscholar   +1 more source

CXCR3/CXCL10 Axis‐Mediated T Cell Infiltration in the Lungs of Patients With HTLV‐1‐Associated Diseases: Implications for Subclinical Pulmonary Involvement

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
Abstract HTLV‐1 is a retrovirus associated with adult T cell leukemia/lymphoma (ATL) and inflammatory diseases, including HTLV‐1‐associated myelopathy (HAM) and HTLV‐1‐associated bronchopneumonopathy (HAB). Although pulmonary complications are common in HTLV‐1‐associated diseases, the underlying mechanisms remain unclear.
Kanako Tsuchimoto, Ayasa Mori, Masakazu Tanaka, Shiho Arishima, Daisuke Kodama, Mika Dozono, Satoshi Nozuma, Hiroshi Takashima, Ryuji Kubota   +8 more
wiley   +1 more source

[Transfection by integrated proviruses].

Voprosy virusologii, 1977
Three lines of continuous mouse L cells were compared: one of them contained only its endogenic oncornavirus, another was contaminated with SV5 virus, and a third was obtained from the second line chronically infected with vesicular stomatitis virus.
G P, Sovetova, M A, Iakhno, B V, Gushchin, U A, Abenova, V D, Solov'ev   +4 more
openaire   +1 more source

Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy

JCI Insight
HIV-1 reservoir cells persist indefinitely during suppressive antiretroviral therapy (ART) in individuals who acquire infection in adulthood, but little is known about the longitudinal evolution of viral reservoir cells during long-term ART started ...
Liliana C. Vela, Leah Carrere, Chloe Naasz, Sruthi Kalavacherla, Toong Seng Tan, Lesley de Armas, Ce Gao, Xu G. Yu, Savita G. Pahwa, Katherine Luzuriaga, Mathias Lichterfeld   +10 more
doaj   +1 more source

Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir

Retrovirology, 2018
Antiretroviral therapy cannot cure HIV-1 infection due to the persistence of a small number of latently infected cells harboring replication-competent proviruses.
Zheng Wang, Francesco R. Simonetti, Robert F. Siliciano, Gregory M. Laird   +3 more
doaj   +1 more source

A novel approach to identify driver genes involved in androgen-independent prostate cancer [PDF]

, 2014
Background Insertional mutagenesis screens have been used with great success to identify oncogenes and tumor suppressor genes. Typically, these screens use gammaretroviruses (γRV) or transposons as insertional mutagens.
Bii, Victor, Meadows, Gary G, Nalla, Arun, Rae, Dustin T, Schinke, Ellyn N, Tedrick, Laura, Trobridge, Grant D   +6 more
core   +2 more sources

Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life

Journal of Virology, 2019
There are limited data about the proviral landscape in children exhibiting long-term suppression after early treatment, particularly in Sub-Saharan Africa where HIV-1 subtype C predominates.
M. Katusiime, E. Halvas, I. Wright, K. Joseph, Michael J. Bale, B. Kirby-McCullough, S. Engelbrecht, W. Shao, Wei-Shau Hu, M. Cotton, J. Mellors, Mary F. Kearney, G. V. Van Zyl   +12 more
semanticscholar   +1 more source

Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans [PDF]

, 2015
Background Approximately 8% of the human genome consists of sequences of retroviral origin, a result of ancestral infections of the germ line over millions of years of evolution.
Cervantes, Patrick, Chan, Susana M, Contreras-Galindo, Rafael, Dai, Manhong, Dube, Derek, Fischer, Sabrina, Kaplan, Mark H, Markovitz, David M, Meng, Fan, Omenn, Gilbert S, Saha, Anjan K, Zahn, Joseph   +11 more
core   +2 more sources

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption

Journal of Virology, 2018
HIV-1 persists as a latent infection in CD4+ T cells that can be found in lymphoid tissues in infected individuals during ART. However, the importance of this tissue reservoir and its contribution to viral rebound upon ART interruption are not clear.
Line K. Vibholm, Julio C. C. Lorenzi, J. Pai, Yehuda Z. Cohen, Thiago Y. Oliveira, J. Barton, Marco Garcia Noceda, Ching-Lan Lu, Y. Ablanedo-Terrazas, P. M. Del Rio Estrada, G. Reyes-Terán, M. Tolstrup, P. W. Denton, T. Damsgaard, O. Søgaard, M. Nussenzweig   +15 more
semanticscholar   +1 more source