Results 71 to 80 of about 13,226 (233)

The HIV-2 proviral landscape is dominated by defective proviruses

open access: yesAIDS, 2023
Background: Compared with HIV-1 infection, HIV-2 infection is associated with a slower progression to AIDS. Understanding the persistence of HIV-2 infection might inform the mechanisms responsible for differences in the pathogenicity of HIV-2 versus HIV-1. Methods: In this study, we
Koofhethile, Catherine K.   +7 more
openaire   +2 more sources

Variant splicing and influence of ionizing radiation on human endogenous retrovirus K (HERV-K) transcripts in cancer cell lines. [PDF]

open access: yesPLoS ONE, 2013
Human endogenous retrovirus K (HERV-K) is the most intact retrovirus in the human genome. There are multiple full-length or near full-length HERV-K proviruses in it.
Lorenzo Agoni, Jack Lenz, Chandan Guha
doaj   +1 more source

Silencing of Unintegrated Retroviral DNAs

open access: yesViruses, 2021
Retroviral infection delivers an RNA genome into the cytoplasm that serves as the template for the synthesis of a linear double-stranded DNA copy by the viral reverse transcriptase.
Stephen P. Goff
doaj   +1 more source

Feline blood donation via cephalic intravenous catheter: A novel method

open access: yesVeterinary Record, EarlyView.
Abstract Background Feline jugular blood donation requires heavy sedation or a very compliant cat. Donation using an intravenous catheter requires less restraint and potentially decreases stress. Methods This was an observational study of feline blood donors at a veterinary hospital between February and June 2023.
Charlotte Russo, Karen Humm
wiley   +1 more source

Mapping of alterations in noninfectious proviruses of spleen necrosis virus [PDF]

open access: yesJournal of Virology, 1981
Ten recombinant lambda phage containing proviruses of spleen necrosis virus (SNV) were previously obtained. Six of the proviruses are infectious and four are not infectious in infectious DNA assays. In this paper, we show that these noninfectious proviruses are not infectious because of alterations in the viral DNA.
J J, O'Rear, H M, Temin
openaire   +2 more sources

NanoHIV: A Bioinformatics Pipeline for Producing Accurate, Near Full-Length HIV Proviral Genomes Sequenced Using the Oxford Nanopore Technology

open access: yesCells, 2021
HIV-1 proviral single-genome sequencing by limiting-dilution polymerase chain reaction (PCR) amplification is important for differentiating the sequence-intact from defective proviruses that persist during antiretroviral therapy (ART).
Imogen A. Wright   +6 more
doaj   +1 more source

Comparison of the Prevalence of Bovine Leukemia Virus (BLV) in Holstein and Angus Cattle Breeds From Shandong Province, China

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Bovine leukemia virus (BLV) is widespread globally and causes economic losses in the cattle industry. Shandong Province plays a significant role in China's livestock industry, with an increasing importance in food of Holstein and Angus cattle. However, BLV prevalence in Holstein and Angus breeds in Shandong Province remains unclear.
Jingyuan Wang   +13 more
wiley   +1 more source

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao   +6 more
wiley   +1 more source

Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy

open access: yesViruses, 2023
HIV establishes a persistent viral reservoir in the brain despite viral suppression in blood to undetectable levels on antiretroviral therapy (ART). The brain viral reservoir in virally suppressed HIV+ individuals is not well-characterized. In this study,
Dana Gabuzda   +4 more
doaj   +1 more source

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

open access: yesCancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

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