Results 81 to 90 of about 9,468 (203)
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Dysfunctional microRNAs and GABAergic interneurons are features of Alzheimer's disease (AD). The role of neuronal microRNA155 (miR155), elevated in both AD and Down syndrome (DS), remains unknown. METHODS We utilized in silico analyses of published databases, MIR155‐deleted and ‐overexpressing human induced pluripotent stem cell ...
Xiaodong Zhu +10 more
wiley +1 more source
, 2007 In vertebrates, Prox1 is homologous to the Drosophila transcription factor, prospero gene. In order to explore Prox1 expression pattern in goldfish, the 2832bp full-length cDNA was cloned, which encodes a protein with 739 amino acids, and the protein ...
Ma Dong-mei +3 more
core
Expression of Prox1 in the adult mouse kidney.
, 2015 (A-C) Single immunostaining for Prox1. Scale bars: 200 μm. Co, cortex; G, glomerulus; AA, arcuate artery; LV, lymphatic vessel. (A’) Inset: higer magnification view of rectangle in A. Scale bars: 10 μm. (D–O) Double immunofluorescence staining for Prox1 (
Yu-mi Kim (741298) +7 more
core +1 more source
SnRNA‐seq reveals cellular heterogeneity and proliferation mechanisms in limb venous malformations
Animal Models and Experimental Medicine, Volume 9, Issue 8, Page 1567-1586, August 2026.To dissect the cellular heterogeneity and invasive mechanisms of limb venous malformations (VMs), this study first obtained tissue samples from four patients with VMs and four normal controls (NC). Single‐nucleus suspension was prepared, followed by transcriptome library construction and sequencing. After pretreatment, quality control, standardization,
Junjie Lin +13 more
wiley +1 more source
PROX1 regulation of endothelial cell cycle progression
The FASEB Journal, 2009 The homeobox transcription factor PROX1 is necessary for proper lymphatic vessel development. PROX1 upregulates the expression of CYCLIN E1 in both Drosophila melanogaster and mammalian cells.
Shannon A Baxter +4 more
openaire +1 more source
Co-expression of PROX1 with cortical interneuron markers.
, 2013 (A) PROX1 is expressed in CR, NPY, RLN and VIP cortical interneurons. Arrows indicate PROX1+ve marker+ve cells, arrowheads indicate PROX1−ve cells. (B) Quantification of the contribution of PROX1+ve cells to each of the marker+ve populations (white), and
Anna Noren Rubin (470529) +1 more
core +1 more source
Frontiers in Cellular Neuroscience, 2015 Over the last decades, adult neurogenesis in the central nervous system (CNS) has emerged as a fundamental process underlying physiology and disease. Recent evidence indicates that the homeobox transcription factor Prox1 is a critical intrinsic regulator
Athanasios eStergiopoulos +2 more
doaj +1 more source
The Role of Prox1 during Mouse Pancreas Organogenesis [PDF]
, 2010 The pancreas is a mixed (exocrine and endocrine) glandular organ that is important for food digestion and glucose homeostasis. Developmental anomalies or disorders that affect normal pancreas homeostasis may cause various life-threatening diseases such ...
Kilic Berkmen, G. (Gamze)
core +1 more source
Representative immunostaining for PROX1 in RCC and adjacent normal tissues.
, 2014 Renal tubular epithelial cells showed intense cytoplasmic PROX1 expression (a). RCC tissues showed variable PROX expression; ccRCC showed low (b), moderate (c), or high (d) PROX1 staining.
Youhua Xie (405867) +9 more
core +1 more source
Cancer Medicine, 2019 Matrix metalloproteinase 14 (MMP14), a membrane‐associated matrix metalloproteinase, has been shown to influence the invasion and metastasis of several solid tumors.
Aaro Kasurinen +10 more
doaj +1 more source