Results 91 to 100 of about 1,097,799 (316)

Proximal Mappings

Journal of Approximation Theory, 1998
The author studies subdifferentiability of the Baire and Mosco-Yosida approximates to a nonconvex function in a Banach space setting. Close results in Hilbert space are given [\textit{F. H. Clarke, R. J. Stern} and \textit{P. R. Wolenski}, J. Convex Anal. 2, No. 1-2, 117-144 (1995; Zbl 0881.49008)].
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Comparative study on outcomes of reverse total shoulder arthroplasty in rotator cuff arthropathy versus nonreconstructable proximal humeral fractures

Alexandria Journal of Medicine
Context Reverse total shoulder arthroplasty (RTSA) has shown great success in treating diverse shoulder ailments. Aims Investigates the clinical outcomes of RTSA in managing rotator cuff arthropathy (RCA) compared to non-reconstructable proximal humeral ...
Mohamed G. Morsy, Ayman S. Ismail, Mohamed M.A. Heif, Omar K.M. Aboelfath Sabbah   +3 more
doaj   +1 more source

The strength of weak proximity

Journal of Discrete Algorithms, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Giuseppe Di Battista, Giuseppe Liotta, Sue Whitesides   +2 more
openaire   +4 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Open Reduction of Neglected Dislocations of the Proximal Interphalangeal Joint

, 2020
Chronic unreduced dislocations of the proximal interphalangeal joint are uncommon and management principles for these injuries have not been defined. The dislocation can be volar or dorsal and closed reduction is rarely successful owing to soft tissue ...
Bamal, R, Bindra, R
core   +1 more source

'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells : modulation of the adherens junction complex by ketamine [PDF]

, 2013
Ketamine, a mild hallucinogenic class C drug, is the fastest growing ‘party drug’ used by 16–24 year olds in the UK. As the recreational use of Ketamine increases we are beginning to see the signs of major renal and bladder complications. To date however,
Claire E Hills, Hills Claire E., Jefferson Kieran P., Squires, Paul E., Issac K-K Liu, Tianrong Jin (452021), Jefferson, Kieran P., Liu, Kuo-Kang, Siamantouras Eleftherios, Siamantouras, Eleftherios, Claire E. Hills (452020), Hills, Claire E., Jin, Tianrong, Eleftherios Siamantouras, Paul E. Squires (452025), Jin Tianrong, Issac K-K Liu (452023), Squires Paul E., Tianrong Jin, Paul E Squires, Liu Issac K-K, Kieran P Jefferson, Kieran P. Jefferson (452024), Eleftherios Siamantouras (452022)   +23 more
core   +1 more source

Proximal Hamstring Repair - Surgical Pearls for the Novice

, 2021
Introduction: Proximal hamstring injuries are rarely encountered sport injuries which cause great functional impairment in the activities of performance.
Samantray, Sikta, Erian, Chris, Connon, Frank, Bajwa, Supreet, Rodda, Daevyd   +4 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source