Results 101 to 110 of about 1,824,701 (322)

Evaluation of efficacy of proximal fibular osteotomy in predominantly medial compartment osteoarthritis of knee for pain relief and improvement in medial joint space of the knee [PDF]

, 2020
Pramod Sunda, AK Mathur, SP Gupta, R S Verma, Mohit Kumar, Narendra Singh   +5 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Proximal humeral metastasis

, 2020
Andrew Dixon
openalex   +1 more source

Proximal and time-varying effects of cigarette, alcohol, marijuana and other hard drug use on adolescent dating aggression

, 2020
Daniel J. Bauer, Vangie A. Foshee, Susan T. Ennett, McNaughton Reyes, H. Luz   +3 more
openalex   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Proximal tibial replacement with megaprosthesis in the setting of proximal tibial nonunion: A case report

Trauma Case Reports
Background: Fracture nonunion is a major concern among an orthopaedic patient population, especially in those who have sustained traumatic fractures involving the tibia. Strong risk factors for nonunion include age, smoking history, and a poor diet.
Ellen Lutnick, Noah M. Braun, Evgeny Dyskin, Mary Bayers-Thering   +3 more
doaj   +1 more source

A Comparative Study of Proximal Femoral Nail and Dynamic Hip Screw in the Treatment of Intertrochanteric Fractures of Femur

, 2022
Muhammad Sarfraz, Saeed Ahmad, Muhammad Shahbaz Raza, Syed Alam Zeb, Sartaj Lakhani, Rahim Khan   +5 more
openalex   +2 more sources

Proximity matters

Proceedings of the National Academy of Sciences, 2022
openaire   +2 more sources