Results 51 to 60 of about 1,721,365 (274)
Deferasirox – a rarer cause of Fanconi syndrome
Journal of Community Hospital Internal Medicine Perspectives, 2019 Deferasirox is a recently approved iron chelator and is widely used to treat iron overload in transfusion-dependent patients. Its once-daily dosing and oral route of administration have made it an appealing alternative to deferoxamine.
Iman Khan, Mustafa Muhammad, Janki Patel
doaj +1 more source
Osteochondral fragments in the metacarpo- and metatarsophalangeal joint and their clinical importance [PDF]
, 2011 The radiographic evaluation of the fetlock joint as part of a lameness or prepurchase examination often reveals osteochondral fragmentation. These fragments can either be causing lameness or have no clinical importance at the time of examination. However,
Declercq, Jeroen +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Clinical relevance of serum lysozyme in sarcoidosis with kidney impairment
Immunological MedicineThe clinical significance of serum lysozyme in sarcoidosis remains unclear. This study aimed to evaluate the clinical characteristics and kidney function of sarcoidosis patients with elevated serum lysozyme.
Shunichiro Hanai +8 more
doaj +1 more source
Convergence Rates of Inexact Proximal-Gradient Methods for Convex Optimization [PDF]
, 2011 We consider the problem of optimizing the sum of a smooth convex function and a non-smooth convex function using proximal-gradient methods, where an error is present in the calculation of the gradient of the smooth term or in the proximity operator with ...
Bach, Francis +2 more
core +5 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Dual-Gate Lumen Model of Renal Monoamine Transport [Expression of Concern]
Neuropsychiatric Disease and Treatment, 2020 Hinz M, Stein A, Uncini T. Neuropsych Dis Treat. 2010;6:387–392. The Editor-in-Chief and Publisher of Neuropsychiatric Disease and Treatment wish to issue an Expression of Concern for the published article.
Hinz M, Stein A, Uncini T
doaj
A Case of Tenofovir-associated Fanconi Syndrome in Patient with Chronic Hepatitis B
The Korean Journal of Gastroenterology, 2016 Tenofovir disoproxil fumarate (TDF) is one of the most widely used treatment options for human immunodeficiency virus (HIV) and HBV infections. Despite its efficacy and safety, some cases of nephrotoxicity have been reported in the treatment of HIV ...
Dongwoo Kim +6 more
doaj +1 more source
Proximal Langevin Sampling with Inexact Proximal Mapping
SIAM Journal on Imaging Sciences29 pages, 11 ...
Matthias J. Ehrhardt +2 more
openaire +4 more sources