Results 101 to 110 of about 53,901 (263)

HucMSC‐Derived Exosomes Preserve Mafb‐Dependent Tubular Epithelial Identity and Suppress Dedifferentiation in Obstructive Nephropathy

Pediatric Discovery, EarlyView.
Unilateral ureteral obstruction (UUO) and genetic deletion of Mafb lead to tubular epithelial dedifferentiation, characterized by decreased E‐cadherin and increased α‐SMA and vimentin expression. Intravenous administration of human umbilical cord mesenchymal stem cell‐derived exosomes (HucMSC‐Exos) partially restores Mafb expression in UUO kidneys ...
Zhuocheng Shi, Chenxi Jia, Meiling Chen, Yihang Yu, Deying Zhang, Guanghui Wei   +5 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

Effect of green tea extract (Camellia sinensis) on kidney toxicity induced by sodium arsenite: a stereological study

مجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Sodium Arsenite is an environmental pollutant which can generate free radicals causing tissue damage. This study was done to evaluate the effect of Green Tea (GTE), as a strong antioxidant, on kidney tissue in mice treated with ...
Shariatzadeh SMA, Soleimani Mehranjani M, Shahmohammadi R, Naderi Noreini S   +3 more
doaj  

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

The predatory behavior of ants: an impressive panoply of morphological adaptations

Insect Science, EarlyView.
This review focuses on predation in ants, showing the wide diversity of cases from solitary foraging to group hunting tactics, as well as the evolution of mandible shape frequently adapted to capture specific prey. Although most ants are generalist feeders, finding their sugary substances directly on plants or indirectly via sap‐sucking insects, some ...
Alain Dejean, Xim Cerdá, Jérôme Orivel, Frédéric Azémar, Alexander L. Wild, Bruno Corbara, Axel Touchard   +6 more
wiley   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Enlarging Fingertip Nodule Mimicking a Pyogenic Granuloma in a Man in his 60's

JEADV Clinical Practice, EarlyView.
Avery H. Seward, Jocelyn H. LaRocque, Stephen M. Hughes   +2 more
wiley   +1 more source

What Outcomes Matter in Vital Pulp Therapy? Current Concepts and Challenges

Australian Dental Journal, EarlyView.
ABSTRACT Vital pulp therapy (VPT) has re‐emerged as a practical and biologically sound alternative for managing deep caries and carious pulp exposures. Although its clinical use is now widespread, the outcomes used to judge the success of VPT remain inconsistent and often difficult to compare across studies.
Philip Yuan‐Ho Chien, Sepanta Hosseinpour, Richard Huynh, Graham Xuanwei Wong, Christine Inge Peters, Ove Andreas Peters   +5 more
wiley   +1 more source