Results 201 to 210 of about 53,118 (291)

By the way, proximal tubule calcium transport [PDF]

American Journal of Physiology-Renal Physiology, 2018
openaire   +3 more sources

Induction of proximal tubular proliferation and lengthening in response to sodium glucose linked cotransporter‐2 inhibition in experimental rats

Journal of Diabetes Investigation, EarlyView.
While SGLT2 accounts for >90% of kidney glucose reabsorption, its pharmacological inhibition or genetic knockdown reduces glucose reabsorption by only 50%. We found that the SGLT2 inhibitor, dapagliflozin, induced an early, transient hyperplastic response in the SGLT1‐expressing S3 segment of the proximal tubule followed by an increase in its length ...
Ellen Wu, Sarah Macklin, Yanling Zhang, Kerri Thai, Linda Nghiem, Caterina Di Ciano‐Oliveira, Nuno Coelho, Hai Wang, Suzanne L. Advani, Jean‐François Desjardins, Darren A Yuen, Paraish Misra, Kim A. Connelly, Jens R. Nyengaard, Richard E. Gilbert   +14 more
wiley   +1 more source

Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease. [PDF]

Nat Commun
Gujarati NA, Frimpong BO, Zaidi M, Bronstein R, Revelo MP, Haley JD, Kravets I, Guo Y, Mallipattu SK.   +8 more
europepmc   +1 more source

Human Bence Jones protein toxicity in rat proximal tubule epithelium in vivo

, 1987
Paul W. Sanders, Guillermo A. Herrera, John H. Galla, Wayne W. Hancock, Robert L. Lott   +4 more
openalex   +1 more source

Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B

Journal of Diabetes Investigation, EarlyView.
Canagliflozin regulated the cyclic guanosine monophosphate (cGMP)‐protein kinase 1‐α signaling pathway through the natriuretic peptide B gene, thereby improving cell viability, apoptosis, and reactive oxygen species levels, and ultimately protecting cardiac function in type 2 diabetic patients with coronary artery disease.
Jiarui Zhang, Lichenlu Huang, Yongqin Zheng, Ji Yang, Xiaopei Wu, Jundong He   +5 more
wiley   +1 more source

Urinary and Serum Amino Acids May Be Associated with Podocyte, Proximal Tubule, and Renal Endothelial Injury in Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients. [PDF]

Biomedicines
Mogos M, Milas O, Socaciu C, Socaciu AI, Vlad A, Gadalean F, Bob F, Cretu OM, Suteanu-Simulescu A, Glavan M, Balint L, Ienciu S, Iancu IL, Jianu DC, Ursoniu S, Petrica L.   +15 more
europepmc   +1 more source

1600 METABOLIC CHANGES IN ENRICHED PROXIMAL TUBULES AFTER ISCHEMIC INJURY [PDF]

, 1985
Karen H Gaudio, Steven R. Gullans, Gunilla Thulin, Thomas Ardito, H Kashqarian, Norman J. Siegel   +5 more
openalex   +1 more source

Clinical use and monitoring of adverse effects of sodium‐glucose cotransporter‐2 inhibitors in persons with type 1 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
Multiple regression analysis revealed that diuretic use was an independent risk factor for discontinuation of SGLT2i. ABSTRACT Aims This study aimed to evaluate the factors contributing to insulin dosage adjustment and the risk of sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) discontinuation in persons with type 1 diabetes mellitus (T1DM) starting ...
Chinatsu Sakai, Shinichi Tamaru, Keiji Sugai, Hironori Takeuchi, Ryo Suzuki   +4 more
wiley   +1 more source

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells. [PDF]

PLoS Pathog
Lorentzen EM, Henriksen S, Rinaldo CH.
europepmc   +1 more source

Evidence for calcium-dependent control of 1,25-dihydroxyvitamin D3 production by rat kidney proximal tubules.

, 1986
Murray J. Favus, Craig B. Langman
openalex   +1 more source