Results 211 to 220 of about 53,118 (291)

The Efficacy and Safety of Canagliflozin by Frailty Status in Participants of the CANVAS and CREDENCE Trials

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Sodium‐glucose cotransporter 2 (SGLT2) inhibitors have been shown to improve renal and cardiovascular outcomes in patients with type 2 diabetes. Limited evidence exists about the efficacy and safety of SGLT2 inhibitors in patients with frailty. Methods This was a post hoc pooled, participant‐level data analysis of the CANVAS Program
Tu N. Nguyen, Jie Yu, Vlado Perkovic, Meg Jardine, Kenneth W. Mahaffey, Clara K. Chow, Clare Arnott, Richard I. Lindley   +7 more
wiley   +1 more source

Yapping at the autophagy door? The answer is flowing in the kidney proximal tubule. [PDF]

Autophagy
Claude-Taupin A, Terzi F, Codogno P, Dupont N.   +3 more
europepmc   +1 more source

Cryo‐SEM and large volume FIB‐SEM of Arabidopsis cotyledons: Degradation of lipid bodies, biogenesis of glyoxysomes and reorganisation of organelles during germination

Journal of Microscopy, EarlyView.
Abstract Until recently, the lack of three‐dimensional visualisation of whole cells at the electron microscopic (EM) level has led to a significant gap in our understanding of the interaction of cellular organelles and their interconnection. This is particularly true with regard to the role of the endoplasmic reticulum (ER).
Gerhard Wanner, Elizabeth Schroeder‐Reiter, Farhah F. Assaad   +2 more
wiley   +1 more source

Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys. [PDF]

Cell Death Discov
Shao X, Xu H, Kim H, Ljaz S, Beier F, Jankowski V, Lellig M, Vankann L, Werner JN, Chen L, Ziegler S, Kuppe C, Zenke M, Schneider RK, Hayat S, Saritas T, Kramann R.   +16 more
europepmc   +1 more source

Lungfish‐like antero‐labial tooth addition and amphibian‐like enameloid‐enamel transition in the coronoid of a Devonian stem actinopterygian

Journal of Anatomy, EarlyView.
The tooth patterning logic, which cannot be inferred from surface morphology, is revealed by visualizing buried tooth remnants in 3D. The primary teeth are added labially, initially organized in radial rows, which transition into linear rows where the coronoid becomes slender.
Donglei Chen
wiley   +1 more source

Efficient proximal tubule-on-chip model from hiPSC-derived kidney organoids for functional analysis of renal transporters. [PDF]

iScience
Ma C, Banan Sadeghian R, Negoro R, Fujimoto K, Araoka T, Ishiguro N, Takasato M, Yokokawa R.   +7 more
europepmc   +1 more source

Elucidating the Proximal Tubule HNF4A Gene Regulatory Network in Human Kidney Organoids.

J Am Soc Nephrol, 2023
Yoshimura Y, Muto Y, Omachi K, Miner JH, Humphreys BD.   +4 more
europepmc   +1 more source

Cell membranes and paracellular resistances in isolated renal proximal tubules from rabbit and Ambystoma.

, 1986
Elsa Bello‐Reuss
openalex   +1 more source

Morphology and development of the baculum in harbour seals (Phoca vitulina)

Journal of Zoology, EarlyView.
This study examines the ontogenetic changes in the morphology of the penis bone in the harbour seal, focusing on the implications for sexual maturity and reproductive function. A large comparative dataset of approx. 300 genital bones from 1 year to over 20 years of age was used for analyses.
T. Berghäuser, J. Wölfer, C. Böhmer, J. A. Nyakatura   +3 more
wiley   +1 more source

Loss of SAV1 in Kidney Proximal Tubule Induces Maladaptive Repair after Ischemia and Reperfusion Injury. [PDF]

Int J Mol Sci
Moon D, Padanilam BJ, Park KM, Kim J.
europepmc   +1 more source