Results 201 to 210 of about 53,901 (263)

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Protocol to develop a proximal tubule-on-chip model based on hiPSC-derived kidney organoids for functional analysis of renal transporters. [PDF]

STAR Protoc
Ma C, Banan Sadeghian R, Negoro R, Fujimoto K, Araoka T, Ishiguro N, Takasato M, Yokokawa R.   +7 more
europepmc   +1 more source

Handling the sugar rush: the role of the renal proximal tubule.

Am J Physiol Renal Physiol
Spellman MJ, Assaf T, Nangia S, Fernandez J, Nicholson KC, Shepard BD.   +5 more
europepmc   +1 more source

How can inhibition of glucose and sodium transport in the early proximal tubule protect the cardiorenal system? [PDF]

Nephrol Dial Transplant
Vallon V.
europepmc   +1 more source

The Kidney Precision Medicine Project and Single-Cell Biology of the Injured Proximal Tubule. [PDF]

Am J Pathol
Janosevic D, De Luca T, Kidney Precision Medicine Project, Eadon MT.   +3 more
europepmc   +1 more source

Thermoforming for Small Feature Replication in Melt Electrowritten Membranes to Model Kidney Proximal Tubule. [PDF]

Adv Healthc Mater
G Valverde M, Stampa Zamorano C, Kožinec D, Benito Zarza L, van Genderen AM, Janssen R, Castilho M, Hrynevich A, Vermonden T, Malda J, de Ruijter M, Masereeuw R, Mihăilă SM.   +12 more
europepmc   +1 more source

Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury.

Am J Physiol Renal Physiol
McElliott MC, Telang AC, Ference-Salo JT, Al-Suraimi A, Chowdhury M, Otto EA, Soofi A, Dressler GR, Beamish JA.   +8 more
europepmc   +1 more source

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Disorders of the Renal Proximal Tubule

Nephron Physiology, 2010
Following glomerular filtration, the bulk of solutes are reabsorbed in the proximal tubule to prevent excessive losses of vital metabolites. In this nephron segment, reabsorption is largely active via dedicated transporters. Hereditary defects in proximal tubular function are characterized by malabsorption affecting amino acids, glucose, potassium ...
Bokenkamp, A., Ludwig, M.
openaire   +3 more sources

The Renal Proximal Tubule

1979
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
M, Silverman, R J, Turner
openaire   +2 more sources

Functional Ultrastructure of the Proximal Tubule

Comprehensive Physiology, 1991
Abstract The sections in this article are: Location of Proximal Tubule Fixation of Proximal Tubule Cells for Electron Microscopy Ultrastructure of the Mammalian Proximal Tubule Cell
Maunsbach, Arvid B., Christensen, Erik Ilsø   +1 more
openaire   +2 more sources