Results 51 to 60 of about 605,238 (303)
Alterations in lysosomal enzymes of the proximal tubule in gentamicin nephrotoxicity [PDF]
, 1991 Alterations in lysosomal enzymes of the proximal tubule in gentamicin nephrotoxicity. Gentamicin accumulates in proximal tubule lysosomes, increases their number, and changes their structure.
Fink, Mathias +2 more
core +1 more source
Proximal renal tubular acidosis with and without Fanconi syndrome
Kidney Research and Clinical Practice, 2019 Proximal renal tubular acidosis (RTA) is caused by a defect in bicarbonate (HCO3−) reabsorption in the kidney proximal convoluted tubule. It usually manifests as normal anion-gap metabolic acidosis due to HCO3− wastage.
Ibrahim Kashoor, Daniel Batlle
doaj +1 more source
Potential and Limits of Kidney Cells for Evaluation of Renal Excretion
Pharmaceuticals, 2021 A large number of therapeutic drugs, herbal components and their metabolites are excreted by the kidneys. Therefore, generally applied models for estimating renal excretion, including freshly isolated rat proximal tubule cells, cultured tubule cells and ...
Christian Lechner +3 more
doaj +1 more source
Anomalous elasticity in nematic and smectic elastomer tubule [PDF]
Phys. Rev. E 78, 031704 (2008), 2008 We study anomalous elasticity in the tubule phases of nematic and smectic elastomer membranes, which are flat in one direction and crumpled in another. These phases share the same macroscopic symmetry properties including spontaneously-broken in-plane isotropy and hence belong to the same universality class.
arxiv +1 more source
Journal of the American Society of Nephrology, 2019 BACKGROUND Sustained activation of EGF receptor (EGFR) in proximal tubule cells is a hallmark of progressive kidney fibrosis after AKI and in CKD. However, the molecular mechanisms and particular EGFR ligands involved are unknown.
Eirini Kefaloyianni +6 more
semanticscholar +1 more source
Segment-specific expression of 2P domain potassium channel genes in human nephron. [PDF]
, 2004 BackgroundThe 2P domain potassium (K2P) channels are a recently discovered ion channel superfamily. Structurally, K2P channels are distinguished by the presence of two pore forming loops within one channel subunit. Functionally, they are characterized by
Bockenhauer, Detlef +3 more
core +1 more source
Membrane tubulation by elongated and patchy nanoparticles [PDF]
Adv. Mater. Interfaces 2016, 1600325, 2016 Advances in nanotechnology lead to an increasing interest in how nanoparticles interact with biomembranes. Nanoparticles are wrapped spontaneously by biomembranes if the adhesive interactions between the particles and membranes compensate for the cost of membrane bending.
arxiv +1 more source
Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis [PDF]
, 2017 Removal of renal mass stimulates anatomical and functional adaptations in the surviving nephrons, including elevations in single-nephron glomerular filtration rate (SNGFR) and tubular hypertrophy. A goal of this study is to assess the extent to which the
Edwards, Aurelie +2 more
core +1 more source
Design Engineering of a Bioartificial Renal Tubule Cell Therapy Device
Cell Transplantation, 1999 The use of a bioartificial renal tubule device composed of renal proximal tubule cells grown within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide more complete replacement therapy of renal function than is ...
Janeta Nikolovski +2 more
doaj +1 more source
Self-assembly of Chiral Tubules [PDF]
Soft Matter 10, 510 (2014), 2013 The efficient and controlled assembly of complex structures from macromolecular building blocks is a critical open question in both biological systems and nanoscience. Using molecular dynamics simulations we study the self-assembly of tubular structures from model macromolecular monomers with multiple binding sites on their surfaces [Cheng et al., Soft
arxiv +1 more source