Results 31 to 40 of about 684,958 (347)
The role of renal proximal tubule transport in the regulation of blood pressure
Kidney Research and Clinical Practice, 2017 The electrogenic sodium/bicarbonate cotransporter 1 (NBCe1) on the basolateral side of the renal proximal tubule plays a pivotal role in systemic acid-base homeostasis.
Shoko Horita +6 more
doaj +1 more source
A modular and reusable model of epithelial transport in the proximal convoluted tubule.
PLoS ONE, 2022 We review a collection of published renal epithelial transport models, from which we build a consistent and reusable mathematical model able to reproduce many observations and predictions from the literature.
Leyla Noroozbabaee +3 more
doaj +1 more source
Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]
, 1998 The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Beck, Franz-X. +4 more
core +1 more source
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury.
Journal of Clinical Investigation, 2019 The proximal tubule has a remarkable capacity for repair after acute injury, but the cellular lineage and molecular mechanisms underlying this repair response are incompletely understood. Here, we developed a Kim1-GFPCreERt2 knockin mouse line (Kim1-GCE)
Monica Chang-Panesso +9 more
semanticscholar +1 more source
Acute effect of prednisolone on renal handling of sodium. [PDF]
, 1973 The effect of prednisolone on renal handling of sodium (Na) was studied in rats under three experimental conditions: 1) hydropenia, 2) water diuresis, and 3) distal tubular blockade (DTB).
Halgrimson, CG +3 more
core +1 more source
Inhalation of mercury vapor can cause the toxic effects on rat kidney [PDF]
, 2016 Dental amalgam has been used in dentistry as a filling material. The filler comprises mercury (Hg). It is considered one of the most important and widespread environmental pollutants, which poses a serious potential threat for the humans and animals ...
Akgul, Hayati Murat +5 more
core +1 more source
Ontogeny of proximal tubule acidification
Kidney International, 1995 The proximal tubule is responsible for the reabsorption of 80% of the filtered load of bicarbonate in adults. Proximal tubule bicarbonate reabsorption is affected by a number of hormones, acid-base balance, and the extracellular fluid volume status [1]. The adult proximal tubule thus plays a central role in acid-base homeostasis.
Baum, Michel, Quigley, Raymond
openaire +2 more sources
Journal of the American Society of Nephrology, 2019 BACKGROUND Proximal tubule injury can initiate CKD, with progression rates that are approximately 50% faster in males versus females. The precise transcriptional changes in this nephron segment during fibrosis and potential differences between sexes ...
Haojia Wu +3 more
semanticscholar +1 more source
PLoS ONE, 2021 The mechanism of pathogenesis associated with APOL1 polymorphisms and risk for non-diabetic chronic kidney disease (CKD) is not fully understood. Prior studies have minimized a causal role for the circulating APOL1 protein, thus efforts to understand ...
Natalya A Blessing +9 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2022 The kidney proximal tubule is responsible for reabsorbing water and NaCl to maintain the homeostasis of the body fluids, electrolytes, and nutrients.
Min Heui Yoo +6 more
doaj +1 more source