Results 61 to 70 of about 605,238 (303)
The goal of this study is to investigate the functional implications of the sexual dimorphism in transporter patterns along the proximal tubule. To do so, we have developed sex-specific computational models of solute and water transport in the proximal ...
Qianyi Li+3 more
semanticscholar +1 more source
There is an alarming global increase in the incidence of end-stage kidney disease, for which early biomarkers and effective treatment options are lacking.
R. Chevalier
semanticscholar +1 more source
The sodium (Na+)/hydrogen (H+) exchanger 3 (NHE3) is one of the most important Na+/H+ antiporters in the small intestines of the gastrointestinal tract and the proximal tubules of the kidney.
Sarah M. Nwia+9 more
doaj +1 more source
Elasticity, Shape Fluctuations and Phase Transitions in the New Tubule Phase of Anisotropic Tethered Membranes [PDF]
We study the shape, elasticity and fluctuations of the recently predicted (cond-mat/9510172) and subsequently observed (in numerical simulations) (cond-mat/9705059) tubule phase of anisotropic membranes, as well as the phase transitions into and out of it.
arxiv +1 more source
Mitochondrial Pathology and Glycolytic Shift during Proximal Tubule Atrophy after Ischemic AKI.
During recovery by regeneration after AKI, proximal tubule cells can fail to redifferentiate, undergo premature growth arrest, and become atrophic. The atrophic tubules display pathologically persistent signaling increases that trigger production of ...
R. Lan+6 more
semanticscholar +1 more source
Acceleration and suppression of banana-shaped-protein-induced tubulation by addition of small membrane inclusions of isotropic spontaneous curvatures [PDF]
The membrane tubulation induced by banana-shaped protein rods is investigated by using coarse-grained meshless membrane simulations. It is found that the tubulation is promoted by laterally isotropic membrane inclusions that generate the same sign of spontaneous curvature as the adsorbed protein rods.
arxiv +1 more source
Theory of Cylindrical Tubules and Helical Ribbons of Chiral Lipid Membranes [PDF]
We present a general theory for the equilibrium structure of cylindrical tubules and helical ribbons of chiral lipid membranes. This theory is based on a continuum elastic free energy that permits variations in the direction of molecular tilt and in the curvature of the membrane.
arxiv +1 more source
Receptor-Mediated Endocytosis in the Proximal Tubule.
Cells lining the proximal tubule (PT) of the kidney are highly specialized for apical endocytosis of filtered proteins and small bioactive molecules from the glomerular ultrafiltrate to maintain essentially protein-free urine.
Megan L. Eshbach, O. Weisz
semanticscholar +1 more source
Three-dimensional structure of basal body triplet revealed by electron cryo-tomography. [PDF]
Basal bodies and centrioles play central roles in microtubule (MT)-organizing centres within many eukaryotes. They share a barrel-shaped cylindrical structure composed of nine MT triplet blades.
Agard, David A+3 more
core +2 more sources
Dispersion of tubules made of diacetylenic phospholipids (DC 8,9 PC), in aqueous colloidal dispersions of magnetic nanoparticles is studied as a function of the sign of particles surface charges. In every case the tubule-vesicle transition temperature is decreased by the presence of the magnetic nanoparticles. Electrophoresis experiments on the tubules
arxiv +1 more source