Results 61 to 70 of about 93,932 (331)
Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]
, 2014 The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto +6 more
core +3 more sources
Advanced Biology, EarlyView.The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
Evaluation of transporter expression in HK-2 cells after exposure to free and ester-bound 3-MCPD
Toxicology Reports, 2021 3-Monochloropropane-1,2-diol (3-MCPD) is a food processing contaminant in some infant formula products and other foods in the United States. Although rodent studies have demonstrated that 3-MCPD and its palmitic esters have the potential to induce ...
Miriam E. Mossoba +4 more
doaj
Grouper tshβ promoter-driven transgenic zebrafish marks proximal kidney tubule development. [PDF]
PLoS ONE, 2014 Kidney tubule plays a critical role in recovering or secreting solutes, but the detailed morphogenesis remains unclear. Our previous studies have found that grouper tshβ (gtshβ) is also expressed in kidney, however, the distribution significance is still
Yang Wang +4 more
doaj +1 more source
Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus [PDF]
, 2017 A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been associated with diabetic nephropathy (DN), but there are no comprehensive studies to date relating early tubulointerstitial injury and the effect of the ...
Bahamonde, Javiera +3 more
core
Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]
, 2018 We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie +2 more
core +1 more source
Ontogeny of NHE8 in the rat proximal tubule [PDF]
American Journal of Physiology-Renal Physiology, 2007 Proximal tubule bicarbonate reabsorption is primarily mediated via the Na+/H+ exchanger, identified as NHE3 in adults. Previous studies have demonstrated a maturational increase in rat proximal tubule NHE3 expression, with a paucity of NHE3 expression in neonates, despite significant Na+-dependent proton secretion. Recently, a novel Na+/H+ antiporter (
Vangipuram Dwarakanath +6 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. [PDF]
, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Agard, David A +3 more
core +1 more source
Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels
Advanced Functional Materials, EarlyView.A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco +12 more
wiley +1 more source