Results 81 to 90 of about 53,118 (291)
Developmental Dynamics, EarlyView.Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel +5 more
wiley +1 more source
Glycosuria and Acute Kidney Injury: A Rare Presentation of Acute Interstitial Nephritis
Kidney Medicine, 2020 Acute interstitial nephritis (AIN) is often induced by drugs and is a common cause of acute kidney injury. Clinically diagnosing AIN can often be challenging because these signs and symptoms rarely present in concert.
Benjamin A. Schwartz, Jason M. Kidd
doaj
The relationship between glomerular filtration rate and sodium reabsorption by the proximal tubule of the rat nephron [PDF]
, 1968 Barry M. Brenner +2 more
openalex +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
Attenuation of SARS-CoV-2 infection by losartan in human kidney organoids
iScience, 2022 Summary: COVID-19-associated acute kidney injury (COVID-AKI) is a common complication of SARS-CoV-2 infection in hospitalized patients. The susceptibility of human kidneys to direct SARS-CoV-2 infection and modulation of the renin-angiotensin II ...
Waleed Rahmani +8 more
doaj
Micropuncture study of hypertonic mannitol diuresis in the proximal and distal tubule of the dog kidney [PDF]
, 1969 J. F. Seely, John H. Dirks
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Comparative Physiology of the Renal Proximal Tubule
Kidney and Blood Pressure Research, 1985 The comparative physiology of the renal proximal tubule (PT) is reviewed in the context of vertebrate evolution and vertebrate strategies of salt and water balance. Though extrarenal machanisms of salt and water balance contribute importantly to extracellular fluid (ECF) homeostasis in the lower vertebrates, the kidney acquires these functions with ...
openaire +3 more sources
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2
Nature CommunicationsThe renal epithelium is sensitive to changes in blood potassium (K+). We identify the basolateral K+ channel, Kir4.2, as a mediator of the proximal tubule response to K+ deficiency.
Yahua Zhang +11 more
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An inhibitory effect of furosemide on sodium reabsorption by the proximal tubule of the rat nephron [PDF]
, 1969 Barry M. Brenner +3 more
openalex +1 more source