Results 21 to 30 of about 159,804 (339)

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill, Ansari AA, Atvinder K. Rullay, Bertozzi CR, Blanch EW, Borchelt D, Caughey B, Caughey B, Caughey B, Caughey BW, Critchley P, David H. Crout, Eberl H, Ferris A, Georges C, Gill AC, Govaerts C, Haire LF, Harris DA, Hornemann S, Ian D. Sylvester, Imanpreet K. Bath, Kazlauskaite J, Kazlauskaite J, Kenyon GL, King SA, Kirby L, Klein TR, Kocienski PJ, Legname G, Matthew R. Hicks, Mui B, Nosjean O, Pan KM, Poss AJ, Safar J, Seddon AM, Shyng SL, Stahl N, Stahl N, Teresa J. T. Pinheiro, Whitesell JK, Wuthrich K, Zahn R, Zhang ZY   +44 more
core   +1 more source

Intra- and interspecies interactions between prion proteins and effects of mutations and polymorphisms [PDF]

, 2003
Recently, crystallization of the prion protein in a dimeric form was reported. Here we show that native soluble homogenous FLAG-tagged prion proteins from hamster, man and cattle expressed in the baculovirus system are predominantly dimeric.
Bradley R., Campbell T.A., Clark W.W., Cutlip R.C., Edenhofer F., Goldfarb L.G., Krasemann S., Leucht C., Lopez L., Majtenyi C., Scott M.R., Weiss S.   +11 more
core   +1 more source

The use of biologics in professional and Olympic sport: a scoping review protocol

Bone & Joint Open, 2020
Aims: The use of biologics in the treatment of musculoskeletal injuries in Olympic and professional athletes appears to be increasing. There are no studies which currently map the extent, range, and nature of existing literature concerning the use and ...
Navnit S. Makaram, Iain R. Murray, Scott A. Rodeo, Seth L. Sherman, Andrew D. Murray, Fares S. Haddad, Timothy R. McAdams, Geoffrey D. Abrams   +7 more
doaj   +1 more source

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

PRP or not PRP? That is the question [PDF]

Knee Surgery, Sports Traumatology, Arthroscopy, 2011
Since the introduction of platelet concentrates as a topical adjuvant therapy to treat chronic leg ulcers in the late 1980, the use of platelet products has been extended to many fields of medicine, with the aim of promoting the healing process of various pathologies in numerous kinds of tissues [5]. Platelet-rich plasma (PRP) and other blood derivates,
KON, ELIZAVETA, FILARDO, GIUSEPPE
openaire   +3 more sources

IVIG Delays Onset in a Mouse Model of Gerstmann-Sträussler-Scheinker Disease [PDF]

, 2019
Our previous studies showed that intravenous immunoglobulin (IVIG) contained anti-Aβ autoantibodies that might be able to treat Alzheimer's disease (AD).
Dodel, Richard, Du, Eileen, Du, Yansheng, Farlow, Martin R., Gu, Huiying, Kirchhein, Yvonne, Liu, Junyi, Mastrianni, James A., Peng, Hongjun, Zhao, Gang, Zhu, Timothy   +10 more
core   +1 more source

Microneedling with platelet-rich plasma versus microneedling with vitamin C in treatment of acne scars: comparative study

Al-Azhar Assiut Medical Journal, 2023
Background and aim Postacne scars may affect about 95% of patients with past history of acne that is related to its duration and severity of. Treatment of acne scarring is challenging.
Khaled M. Tawfik, Mahmoud A.E. Makki, Fatma E.-Z.M. Mahmoud   +2 more
doaj   +1 more source

Some are Punished and Some are Rewarded: A Study of the Impact of Performance Pay on Job Satisfaction [PDF]

, 2007
Using an econometric procedure that corrects for both self-selection of individuals into their preferred compensation scheme and wage endogeneity, this study investigates whether significant differences exist in the job satisfaction of individuals ...
McCausland, W. David, Pouliakas, Kostas, Theodossiou, Ioannis   +2 more
core   +1 more source

Gamma Low-Dose-Rate Ionizing Radiation Stimulates Adaptive Functional and Molecular Response in Human Aortic Endothelial Cells in a Threshold-, Dose-, and Dose Rate–Dependent Manner

Dose-Response, 2018
A central question in radiation protection research is whether low-dose and low-dose-rate (LDR) exposures to ionizing radiation play a role in progression of cardiovascular disease.
Juliana Vieira Dias, Celine Gloaguen, Dimitri Kereselidze, Line Manens, Karine Tack, Teni G Ebrahimian   +5 more
doaj   +1 more source

High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age [PDF]

, 2009
Following a severe outbreak of clinical scrapie in 2006–2007, a large dairy goat herd was culled and 200 animals were selected for post-mortem examinations in order to ascertain the prevalence of infection, the effect of age, breed and PRNP genotype on
Dawson, M., Goldmann, W., Gonzalez, L., Hawkins, S. A., Hope, J., Jeffrey, M., Konold, T., Martin, S., Ortiz-Pelaez, A., Phelan, L., Saunders, G., Siso, S., Stewart, P., Windl, O.   +13 more
core   +3 more sources