Results 41 to 50 of about 49,654 (267)

Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis [PDF]

Veterinarski Glasnik, 2020
Introduction. In order to provide the most favorable conditions for bone healing following implant loading, new techniques such as the use of growth factors to directly or indirectly regulate cell and tissue growth are becoming increasingly popular ...
Duka Miloš, Lazić Zoran, Bubalo Marija, Mihailović Branko, Miladinović Milan, Gvozdić Dragan   +5 more
doaj   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Evidence of health inequities across the rare disease patient care pathway: development of a toolkit using a conceptual framework

Orphanet Journal of Rare Diseases
People with a rare disease (PwRD) often face more challenges than the wider population in obtaining a diagnosis and accessing services. These challenges can be framed as health inequities, i.e.
Simon Briscoe, Clara Martin Pintado, Ruth Garside, Jo Thompson Coon, Hassanat M. Lawal, Noreen Orr, Liz Shaw, G. J. Melendez-Torres   +7 more
doaj   +1 more source

Primary care clinicians’ perspectives on interacting with patients with gynaecological conditions: a systematic review

BJGP Open
Background: Studies have found that women with gynaecological conditions and symptoms do not feel listened to by primary care clinicians (PCCs). Less understood is whether PCCs perceive that there are challenges around listening to and interacting with ...
Simon Briscoe, Jo Thompson Coon, G J Melendez-Torres, Rebecca Abbott, Liz Shaw, Michael Nunns, Ruth Garside   +6 more
doaj   +1 more source

The role of PRP and adipose tissue-derived keratinocytes on burn wound healing in diabetic rats [PDF]

BioImpacts, 2018
Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients. The aim of this study is to investigate the use of platelet rich-plasma (PRP) and/or keratinocyte-like cells (KLCs) in diabetic thermal wound rat model and ...
Navid Hosseini Mansoub, Mehmet Gürdal, Elif Karadadaş, Hilal Kabadayi, Seda Vatansever, Gulinnaz Ercan   +5 more
doaj   +1 more source

The effectiveness of platelet-rich plasma gel on full-thickness cartilage defect repair in a rabbit model

Bone & Joint Research, 2021
Aims: The present study investigates the effectiveness of platelet-rich plasma (PRP) gel without adjunct to induce cartilage regeneration in large osteochondral defects in a rabbit model.
Fathia Slimi, Wassim Zribi, Moez Trigui, Raja Amri, Nawrez Gouiaa, Cyrine Abid, Mohammed Ali Rebai, Tahia Boudawara, Samira Jebahi, Hassib Keskes   +9 more
doaj   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Crestal bone loss around dental implants after implantation of Tricalcium phosphate and Platelet- Rich Plasma: A comparative study

Journal of Family Medicine and Primary Care, 2020
Background and Aims: Bone loss around dental implants is generally measured by monitoring changes in marginal bone level using radiographs. After the first year of implantation, an implant should have
Sravani Uppala, Anuj Singh Parihar, Varsha Modipalle, Litto Manual, Vinni Mary Oommen, Pallavi Karadiguddi, Parkhi Gupta   +6 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Platelet-rich plasma in clinical practice

South African Family Practice, 2016
The concept of using a patient’s own blood or components thereof (autologous), to enhance the physiological process of healing has been in place for many years. Autologous platelet-rich plasma (PRP) has been used for both soft tissue and bone healing and
Heidi Siebert
doaj   +1 more source