Results 51 to 60 of about 83,022 (311)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Terapias alternativas en condromalacia patelar: estudio comparativo entre la terapia con plasma rico en plaquetas (prp), endoret y acido hialuronico, abril 2022 a octubre 2022

open access: yesRevista Científica CMDLT, 2022
Introducción: el presente trabajo tuvo como objetivo de comparar y analizar la eficacia de las terapias alternativas en condromalacia patelar (terapia con plasma rico en plaquetas, endoret y ácido hialurónico) y determinar si tendremos un tratamiento ...
Jonathan Vásquez Castellano   +1 more
doaj   +2 more sources

Short‐Term Outcomes of Two Interventions for Patients With Active Proliferative Diabetic Retinopathy in an Urban, Safety‐Net Hospital [PDF]

open access: yesHealth Care Sci
An additional weekly resident‐run panretinal photocoagulation (PRP) clinic and implementation of a high‐risk registry and appointment system were associated with a decreased wait time from proliferative diabetic retinopathy (PDR) diagnosis to PRP, increased 3‐month PRP completion rates, decreased 3‐month loss to follow‐up, and increased ophthalmology ...
Micevych P, Taha A, Kumar A, Stewart J.
europepmc   +2 more sources

PRP Augmentation for ACL Reconstruction [PDF]

open access: yesBioMed Research International, 2015
Current research is investigating new methods to enhance tissue healing to speed up recovery time and decrease the risk of failure in Anterior Cruciate Ligament (ACL) reconstructive surgery. Biological augmentation is one of the most exploited strategies, in particular the application of Platelet Rich Plasma (PRP).
ANDRIOLO, LUCA   +5 more
openaire   +3 more sources

Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon [PDF]

open access: yes, 1991
Current models of the virus-like agents of scrapie and bovine spongiform encephalopathy (BSE) have to take into account that structural changes in a host-encoded protein (PrP protein) exhibit an effect on the time course of these diseases and the ...
Dawson, M   +9 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Conformational Properties of β-PrP [PDF]

open access: yesJournal of Biological Chemistry, 2009
Prion propagation involves a conformational transition of the cellular form of prion protein (PrPC) to a disease-specific isomer (PrPSc), shifting from a predominantly alpha-helical conformation to one dominated by beta-sheet structure. This conformational transition is of critical importance in understanding the molecular basis for prion disease. Here,
Hosszu, Laszlo L P   +8 more
openaire   +2 more sources

Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice [PDF]

open access: yes, 2009
Background: Prionopathies are characterized by spongiform brain degeneration, myoclonia, dementia, and periodic electroencephalographic (EEG) disturbances.
Delgado-García, J. M.   +39 more
core   +1 more source

New AI‐Assisted Approach for Expanding the Solution Space: Application to Lattice Structure Design

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces an innovative framework for designing structured materials by ex panding the design space through reparameterization of qualitative variables into continuous structural descriptors. Combined with machine‐learning‐based prediction and multi‐objective optimization, the approach enables the discovery of novel lattice architectures ...
G. H. Gahimbare   +5 more
wiley   +1 more source

Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model

open access: yesVeterinární Medicína, 2016
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues.
J. Vokurka   +4 more
doaj   +1 more source

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