Cancer and non-cancer mortality among French uranium cycle workers: the TRACY cohort
Objectives The health effects of internal contamination by radionuclides, and notably by uranium, are poorly characterised. New cohorts of uranium workers are needed to better examine these effects.
David B Richardson +7 more
doaj +1 more source
Role of PrP in prion diseases [PDF]
Note: Weissmann, C. Univ Zurich,Inst Molek Biol I,Ch-8006 Zurich,Switzerland Univ Tatsspital Zurich,Inst Neuropathol,Zurich,Switzerland Reference UPAGU-ARTICLE-1993-007 Record created on 2007-12-12, modified on 2017-05 ...
Weissmann, C +5 more
openaire +5 more sources
Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Hicks, M R +13 more
core +1 more source
On the issue of obtaining platelet-rich plasma
Objective: To determine the optimal technological modes for the preparation of platelet-rich plasma (PRP) using standard laboratory equipment.Material and methods: Blood for the research was taken from 25 healthy volunteers.
S. B. Bazlov +5 more
doaj +1 more source
The crystal structure of the globular domain of sheep prion protein [PDF]
The prion protein PrP is a naturally occurring polypeptide that becomes transformed from a normal conformation to that of an aggregated form, characteristic of pathological states in fatal transmissible spongiform conditions such as Creutzfeld–Jacob ...
Vasisht N +28 more
core +1 more source
Histopathological study of the effect of using repeated doses of platelets-rich plasma on articular cartilage repair in Rabbits [PDF]
The present study was performed on platelet-rich plasma compound from animals engaged in this work, to be directly injected in the joint space of the affected stifle joint 5mm diameter full-thickness articular cartilage removal in the knee joint manually
Mustafa A. Khaleefa, Hasanain A. Emran
doaj +1 more source
Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob disease [PDF]
In recent studies, the amyloid form of recombinant prion protein (PrP) encompassing residues 89-230 (rPrP 89-230) produced in vitro induced transmissible prion disease in mice.
Bocharova, O V +9 more
core +1 more source
Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding [PDF]
Transmissible spongiform encephalopathies, or prion diseases, are caused by misfolding and aggregation of the prion protein PrP. These diseases can be hereditary in humans and four of the many disease-associated missense mutants of PrP are in the ...
Valerie Daggett +3 more
core +1 more source
Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review [PDF]
Premature ovarian failure (POF), is a condition characterized by the early decline of ovulation function. POF is a complex disorder that can be caused by various factors, and the idiopathic form represents a significant proportion of POF patients ...
Yahya Yahyavi +9 more
doaj +1 more source
Scrapie-resistant sheep show certain coat colour characteristics [PDF]
Susceptibility to scrapie is known to be associated with polymorphisms at the prion protein (PrP) gene, and this association is the basis of current selective programmes implemented to control scrapie in many Countries.
White, I +11 more
core +1 more source

