Efficacy of platelet-rich plasma as conservative treatment in orthopaedics. a systematic review and meta-analysis [PDF]
Background. The aim of this systematic review and meta-analysis was to evaluate the benefit of platelet-rich plasma (PRP) in non-surgical orthopaedic procedures. Material and methods. We searched the Cochrane Wounds Specialized Register, CENTRAL, MEDLINE
Cruciani, Mario +9 more
core +1 more source
Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding [PDF]
Transmissible spongiform encephalopathies, or prion diseases, are caused by misfolding and aggregation of the prion protein PrP. These diseases can be hereditary in humans and four of the many disease-associated missense mutants of PrP are in the ...
Daggett, Valerie, van der Kamp, Marc W
core +2 more sources
Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep [PDF]
The aim of this study was to characterize the cerebrospinal fluid (CSF) prion protein (PrP) of healthy and naturally scrapie-affected sheep. The soluble form of CSF PrPC immunoblotted with an anti-octarepeat and an anti-C terminus mAb showed two isoforms
Andréoletti +24 more
core +3 more sources
Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review [PDF]
Premature ovarian failure (POF), is a condition characterized by the early decline of ovulation function. POF is a complex disorder that can be caused by various factors, and the idiopathic form represents a significant proportion of POF patients ...
Yahya Yahyavi +9 more
doaj +1 more source
Plasma rich-platelet (PRP) potentially attenuates tamoxifen spermatogenic dysfunction in rat's model: sperm quality, histomorphometric, and apoptosis assessment [PDF]
Background: Tamoxifen induces testicular atrophy and azoospermia. Conversely, platelet-rich plasma (PRP) is a distinctive analog yield enriched with cytokines and growth factors for improving tissue regeneration.
Hossein Hamali +3 more
doaj +1 more source
Identifying Moderators Of Response To The Penn Resiliency Program: A Synthesis Study [PDF]
To identify moderators of a cognitive-behavioral depression prevention program’s effect on depressive symptoms among youth in early adolescence, data from three randomized controlled trials of the Penn Resiliency Program (PRP) were aggregated to maximize
Brunwasser, S. M., Gillham, Jane
core +2 more sources
Platelet-rich plasma (PRP) has been a focus of researchers and clinicians for quite some time with mixed results reported. From stunning laboratory animal success to disappointing clinical studies, a clear picture has not emerged.2 Yet, the enthusiasm for cell-based therapies is understandable.
openaire +2 more sources
Osteochondral Lesion of Talus: Role of Bone Marrow Aspirate Concentrate and Microfracture—What Does the Current Literature Say? [PDF]
Osteochondral lesions (OCL) are increasingly being identified at present. These lesions include both osteochondritis dissecans (OCD) and osteochondral fractures.
Prateek Behera +2 more
doaj +1 more source
Purpose: To evaluate the outcomes of patients who had osteochondral lesions of the talus treated with osteochondral allograft transplants combined with platelet-rich plasma (PRP) and hyaluronic acid (HA).
George A. Rublev, M.D. +11 more
doaj +1 more source
Purpose: To evaluate the experiences and outcomes of arthroscopic partial meniscectomy in symptomatic non-Wrisberg discoid lateral meniscus in children younger than 12 years old at a single center. Methods: We retrospectively reviewed the medical records
George A. Rublev, M.D. +6 more
doaj +1 more source

