Results 21 to 30 of about 49,925 (266)

Interaction between Shadoo and PrP Affects the PrP-Folding Pathway [PDF]

Journal of Virology, 2015
ABSTRACT Prion diseases are characterized by conformational changes of a cellular prion protein (PrP C ) into a β-sheet-enriched and aggregated conformer (PrP Sc ). Shadoo (Sho), a member of the prion protein family, is expressed in the central nervous system (CNS) and is highly ...
Ciric, Danica, Richard, Charles-Adrien, Moudjou, Mohammed, Chapuis, Jérôme, Sibille, Pierre, Daude, Nathalie, Westaway, David, Adrover, Miguel, Béringue, Vincent, Martin, Davy, Rezaei, Human   +10 more
openaire   +3 more sources

Management of Fibrosis: The Mesenchymal Stromal Cells Breakthrough

Stem Cells International, 2014
Fibrosis is the endpoint of many chronic inflammatory diseases and is defined by an abnormal accumulation of extracellular matrix components. Despite its slow progression, it leads to organ malfunction. Fibrosis can affect almost any tissue.
Benoît Usunier, Marc Benderitter, Radia Tamarat, Alain Chapel   +3 more
doaj   +1 more source

Cancer and non-cancer mortality among French uranium cycle workers: the TRACY cohort

BMJ Open, 2016
Objectives The health effects of internal contamination by radionuclides, and notably by uranium, are poorly characterised. New cohorts of uranium workers are needed to better examine these effects.
David B Richardson, Dominique Laurier, Eric Samson, Irwin Piot, Sergey Zhivin, Pierre Laroche, Ana-Paula Serond, Olivier Laurent   +7 more
doaj   +1 more source

Role of PrP in prion diseases [PDF]

British Medical Bulletin, 1993
Note: Weissmann, C. Univ Zurich,Inst Molek Biol I,Ch-8006 Zurich,Switzerland Univ Tatsspital Zurich,Inst Neuropathol,Zurich,Switzerland Reference UPAGU-ARTICLE-1993-007 Record created on 2007-12-12, modified on 2017-05 ...
Weissmann, C, Büeler, H, Sailer, A, Fischer, M, Aguet, M, Aguzzi, A   +5 more
openaire   +5 more sources

On the issue of obtaining platelet-rich plasma

Инновационная медицина Кубани, 2022
Objective: To determine the optimal technological modes for the preparation of platelet-rich plasma (PRP) using standard laboratory equipment.Material and methods: Blood for the research was taken from 25 healthy volunteers.
S. B. Bazlov, K. I. Melkonian, T. V. Rusinova, K. I. Popandopulo, N. V. Marchenko, D. D. Shevchuk   +5 more
doaj   +1 more source

Histopathological study of the effect of using repeated doses of platelets-rich plasma on articular cartilage repair in Rabbits [PDF]

Iraqi Journal of Veterinary Sciences, 2022
The present study was performed on platelet-rich plasma compound from animals engaged in this work, to be directly injected in the joint space of the affected stifle joint 5mm diameter full-thickness articular cartilage removal in the knee joint manually
Mustafa A. Khaleefa, Hasanain A. Emran
doaj   +1 more source

PrP Conformational Transitions Alter Species Preference of a PrP-specific Antibody [PDF]

Journal of Biological Chemistry, 2010
The epitope of the 3F4 antibody most commonly used in human prion disease diagnosis is believed to consist of residues Met-Lys-His-Met (MKHM) corresponding to human PrP-(109-112). This assumption is based mainly on the observation that 3F4 reacts with human and hamster PrP but not with PrP from mouse, sheep, and cervids, in which Met at residue 112 is ...
Zou, W.Q., Langeveld, J.P.M., Xiao, X., Chen, S., McGeer, P.L., Yuan, J., Payne, M.C., Kang, H.E., McGeehan, J.M., Sy, M.S., Greenspan, N.S., Kaplan, D., Wang, G.X., Parchi, P., Hoover, E.A., Kneale, G., Telling, G., Surewicz, W., Kong, Q., Guo, J.   +19 more
openaire   +3 more sources

Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review [PDF]

Advanced Pharmaceutical Bulletin
Premature ovarian failure (POF), is a condition characterized by the early decline of ovulation function. POF is a complex disorder that can be caused by various factors, and the idiopathic form represents a significant proportion of POF patients ...
Yahya Yahyavi, Niloufar Kheradi, Abbas Karimi, Abbas Ebrahimi-Kalan, Fatemeh Ramezani, Soudabe Yousefi, Shirin Teymouri Nobari, Hourieh Sadrekarimi, Mohammad Nouri, Mahdi Edalati   +9 more
doaj   +1 more source

PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection [PDF]

Journal of Virology, 2017
ABSTRACT Glycosylphosphatidylinositol (GPI) anchoring of the prion protein (PrP C ) influences PrP C misfolding into the disease-associated isoform, PrP res , as well as prion propagation and infectivity.
Marshall KE, Hughson A, Vascellari S, Priola SA, Sakudo A, Onodera T, Baron GS   +6 more
openaire   +2 more sources

Plasma rich-platelet (PRP) potentially attenuates tamoxifen spermatogenic dysfunction in rat's model: sperm quality, histomorphometric, and apoptosis assessment [PDF]

Asia Pacific Journal of Medical Toxicology
Background: Tamoxifen induces testicular atrophy and azoospermia. Conversely, platelet-rich plasma (PRP) is a distinctive analog yield enriched with cytokines and growth factors for improving tissue regeneration.
Hossein Hamali, Fatemeh Masoumi, Behzad Baradaran, Gholamreza Hamidian   +3 more
doaj   +1 more source