Cell Transplantation, 2016 Ionizing radiation is effective to treat malignant pelvic cancers, but the toxicity to surrounding healthy tissue remains a substantial limitation. Early and late side effects not only limit the escalation of the radiation dose to the tumor but may also ...
Lara Moussa +6 more
doaj +1 more source
IVIG Delays Onset in a Mouse Model of Gerstmann-Sträussler-Scheinker Disease [PDF]
, 2019 Our previous studies showed that intravenous immunoglobulin (IVIG) contained anti-Aβ autoantibodies that might be able to treat Alzheimer's disease (AD).
Dodel, Richard +10 more
core +1 more source
Prion protein interacts with bace1 and differentially regulates its activity towards wild type and swedish mutant amyloid precursor protein [PDF]
, 2011 In Alzheimer disease amyloid-β (Aβ) peptides derived from the amyloid precursor protein (APP) accumulate in the brain. Cleavage of APP by the β-secretase BACE1 is the rate-limiting step in the production of Aβ.
Andersen +49 more
core +1 more source
Management of Fibrosis: The Mesenchymal Stromal Cells Breakthrough
Stem Cells International, 2014 Fibrosis is the endpoint of many chronic inflammatory diseases and is defined by an abnormal accumulation of extracellular matrix components. Despite its slow progression, it leads to organ malfunction. Fibrosis can affect almost any tissue.
Benoît Usunier +3 more
doaj +1 more source
Cancer and non-cancer mortality among French uranium cycle workers: the TRACY cohort
BMJ Open, 2016 Objectives The health effects of internal contamination by radionuclides, and notably by uranium, are poorly characterised. New cohorts of uranium workers are needed to better examine these effects.
David B Richardson +7 more
doaj +1 more source
On the issue of obtaining platelet-rich plasma
Инновационная медицина Кубани, 2022 Objective: To determine the optimal technological modes for the preparation of platelet-rich plasma (PRP) using standard laboratory equipment.Material and methods: Blood for the research was taken from 25 healthy volunteers.
S. B. Bazlov +5 more
doaj +1 more source
Histopathological study of the effect of using repeated doses of platelets-rich plasma on articular cartilage repair in Rabbits [PDF]
Iraqi Journal of Veterinary Sciences, 2022 The present study was performed on platelet-rich plasma compound from animals engaged in this work, to be directly injected in the joint space of the affected stifle joint 5mm diameter full-thickness articular cartilage removal in the knee joint manually
Mustafa A. Khaleefa, Hasanain A. Emran
doaj +1 more source
High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age [PDF]
, 2009 Following a severe outbreak of clinical scrapie in 2006–2007, a large dairy goat herd was culled and 200 animals were selected for post-mortem examinations in order to ascertain the prevalence of infection, the effect of age, breed and PRNP genotype on
Dawson, M. +13 more
core +3 more sources
Assessment of the Composition and Biologic Activity of Platelet Rich Plasma and its Relationship to Clinical Outcomes in Patients with Knee Osteoarthritis [PDF]
, 2020 Recent studies suggest positive clinical outcomes associated with platelet-rich-plasma (PRP) administration to treat knee osteoarthritis (OA). However, the results remain inconclusive in part because of the high variability in PRP preparations and the ...
Bhandhari, Reyna +12 more
core +1 more source
Some are Punished and Some are Rewarded: A Study of the Impact of Performance Pay on Job Satisfaction [PDF]
, 2007 Using an econometric procedure that corrects for both self-selection of individuals into their preferred compensation scheme and wage endogeneity, this study investigates whether significant differences exist in the job satisfaction of individuals ...
McCausland, W. David +2 more
core +1 more source