Results 11 to 20 of about 153,463 (312)

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill, Ansari AA, Atvinder K. Rullay, Bertozzi CR, Blanch EW, Borchelt D, Caughey B, Caughey B, Caughey B, Caughey BW, Critchley P, David H. Crout, Eberl H, Ferris A, Georges C, Gill AC, Govaerts C, Haire LF, Harris DA, Hornemann S, Ian D. Sylvester, Imanpreet K. Bath, Kazlauskaite J, Kazlauskaite J, Kenyon GL, King SA, Kirby L, Klein TR, Kocienski PJ, Legname G, Matthew R. Hicks, Mui B, Nosjean O, Pan KM, Poss AJ, Safar J, Seddon AM, Shyng SL, Stahl N, Stahl N, Teresa J. T. Pinheiro, Whitesell JK, Wuthrich K, Zahn R, Zhang ZY   +44 more
core   +1 more source

The use of biologics in professional and Olympic sport: a scoping review protocol

Bone & Joint Open, 2020
Aims: The use of biologics in the treatment of musculoskeletal injuries in Olympic and professional athletes appears to be increasing. There are no studies which currently map the extent, range, and nature of existing literature concerning the use and ...
Navnit S. Makaram, Iain R. Murray, Scott A. Rodeo, Seth L. Sherman, Andrew D. Murray, Fares S. Haddad, Timothy R. McAdams, Geoffrey D. Abrams   +7 more
doaj   +1 more source

PRP or not PRP? That is the question [PDF]

Knee Surgery, Sports Traumatology, Arthroscopy, 2011
Since the introduction of platelet concentrates as a topical adjuvant therapy to treat chronic leg ulcers in the late 1980, the use of platelet products has been extended to many fields of medicine, with the aim of promoting the healing process of various pathologies in numerous kinds of tissues [5]. Platelet-rich plasma (PRP) and other blood derivates,
KON, ELIZAVETA, FILARDO, GIUSEPPE
openaire   +3 more sources

HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons [PDF]

, 2013
Platelet-rich plasma (PRP) containing hepatocyte growth factor (HGF) and other growth factors are widely used in orthopaedic/sports medicine to repair injured tendons.
A Mishra, A Schneider, AR Amin, B Christensen, B Christensen, BA Kerr, C Gabay, C Hsu, C Molnar, Cristoforo Scavone, DL Butler, DW Gilroy, DW Gilroy, E Anitua, E Homsi, F Cilli, Freddie H. Fu, G Yang, H El-Sharkawy, Hee-Jeong Im, J Damm, J Zhang, J Zhang, J Zhang, J Zhang, James H-C. Wang, JC Peerbooms, JC Peerbooms, JH Wang, JH Wang, Jianying Zhang, K Takai, Kellie K. Middleton, KM Khan, L Engebretsen, LC Almekinders, M Giannopoulou, M Okada, M Tsuzaki, MH Khan, MM Murray, MM Murray, MM Wolfe, P Bendinelli, P Renstrom, R Gong, RE Marx, RJ de Vos, S Fiorucci, S Nakamura, S Narumiya, SH Ferreira, ST Ferry, T Kaido, T Molloy, TE Foster, TJ Williams, U Sheth, UC Kopp, WL Smith, YH Kang, Z Li   +61 more
core   +1 more source

Microneedling with platelet-rich plasma versus microneedling with vitamin C in treatment of acne scars: comparative study

Al-Azhar Assiut Medical Journal, 2023
Background and aim Postacne scars may affect about 95% of patients with past history of acne that is related to its duration and severity of. Treatment of acne scarring is challenging.
Khaled M. Tawfik, Mahmoud A.E. Makki, Fatma E.-Z.M. Mahmoud   +2 more
doaj   +1 more source

Analysis of platelet-rich plasma extraction variations in platelet and blood components between 4 common commercial kits [PDF]

, 2017
Background: Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP. Purpose:
Bulsara, MK, Fitzpatrick, J, McCrory, PR, Richardson, MD, Zheng, MH   +4 more
core   +2 more sources

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

Gamma Low-Dose-Rate Ionizing Radiation Stimulates Adaptive Functional and Molecular Response in Human Aortic Endothelial Cells in a Threshold-, Dose-, and Dose Rate–Dependent Manner

Dose-Response, 2018
A central question in radiation protection research is whether low-dose and low-dose-rate (LDR) exposures to ionizing radiation play a role in progression of cardiovascular disease.
Juliana Vieira Dias, Celine Gloaguen, Dimitri Kereselidze, Line Manens, Karine Tack, Teni G Ebrahimian   +5 more
doaj   +1 more source

Prion degradation pathways: Potential for therapeutic intervention [PDF]

, 2015
Prion diseases are fatal neurodegenerative disorders. Pathology is closely linked to the misfolding of native cellular PrP(C) into the disease-associated form PrP(Sc) that accumulates in the brain as disease progresses. Although treatments have yet to be
Goold, R, McKinnon, C, Tabrizi, SJ
core   +1 more source

PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection [PDF]

Journal of Virology, 2017
ABSTRACT Glycosylphosphatidylinositol (GPI) anchoring of the prion protein (PrP C ) influences PrP C misfolding into the disease-associated isoform, PrP res , as well as prion propagation and infectivity.
Marshall KE, Hughson A, Vascellari S, Priola SA, Sakudo A, Onodera T, Baron GS   +6 more
openaire   +2 more sources