Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP [PDF]
, 2003 The prion protein (PrP) plays a central role in prion diseases, and identifying its cellular receptor appears to be of crucial interest. We previously showed in the yeast twohybrid system that PrP interacts with the 37 kDa precursor (LRP) of the high ...
S. Weiss +13 more
core +3 more sources
The role of host PrP in Transmissible Spongiform Encephalopathies [PDF]
, 2007 PrP has a central role in the Transmissible Spongiform Encephalopathies (TSEs), and mutations and polymorphisms in host PrP can profoundly alter the host's susceptibility to a TSE agent.
Barron, Rona M +10 more
core +1 more source
Evaluation of the Hydroxyproline Content in the Frozen Allograft Tendon Impregnated with the Mesenchymal Cells & PRP in Lamb [PDF]
Iranian Journal of Veterinary Medicine, 2019 Background: Tendon grafting is mostly required to repair an injury to flexor tendon and due to the importance of this tendon; it needs methods to speed up the re-vitality of the tendon allograft. OBJECTIVES: The aim was to investigate the efficacy of the
Rafid Naeem Majid Alkhalifa +6 more
doaj +1 more source
Comparative efficacy of platelet-rich plasma and dextrose prolotherapy for stifle joint arthritis in a rabbit model [PDF]
Iraqi Journal of Veterinary Sciences, 2023 This study aimed to investigate the efficacy of PRP and dextrose PRL in stifle joint arthritis in rabbits.Sixteen healthy adult male rabbits were allocated into groups A (n=8) and B (n=8).
Fawad Khalil +8 more
doaj +1 more source
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). [PDF]
, 2013 Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans.
Jeremy C. Simpson (29225) +31 more
core +2 more sources
A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres [PDF]
, 2006 Prion diseases are associated with the conversion of the normal cellular prion protein, PrPC, to the abnormal, disease-associated form, PrPSc. This conversion can be mimicked in vitro by using a cell-free conversion assay. It has recently been shown that
Kirby, Louise +4 more
core +1 more source
The use of biologics in professional and Olympic sport: a scoping review protocol
Bone & Joint Open, 2020 Aims: The use of biologics in the treatment of musculoskeletal injuries in Olympic and professional athletes appears to be increasing. There are no studies which currently map the extent, range, and nature of existing literature concerning the use and ...
Navnit S. Makaram +7 more
doaj +1 more source
Sports Health: A Multidisciplinary Approach, 2012 Platelet-rich plasma (PRP) has been a focus of researchers and clinicians for quite some time with mixed results reported. From stunning laboratory animal success to disappointing clinical studies, a clear picture has not emerged.2 Yet, the enthusiasm for cell-based therapies is understandable.
openaire +2 more sources
PrP-C and PrP-Sc at the Fetal-Maternal Interface [PDF]
Journal of Biological Chemistry, 2001 Scrapie is a naturally occurring prion (PrP) disease causing a fatal neurodegenerative disorder in sheep and goats. Previous studies suggest that scrapie is transmitted naturally through exposure to the scrapie agent in wasted placentas of infected ewes.
Tuo, Wenbin +5 more
openaire +3 more sources
Al-Azhar Assiut Medical Journal, 2023 Background and aim Postacne scars may affect about 95% of patients with past history of acne that is related to its duration and severity of. Treatment of acne scarring is challenging.
Khaled M. Tawfik +2 more
doaj +1 more source