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Physiological role of the normal cellular prion protein (PrPC)

2014
na
Govindarajan, Nambirajan   +2 more
openaire   +1 more source

[Cloning and sequencing of the Chinese bovine prion protein (PrPC) gene].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2003
The total DNA was isolated from lymphocyte of peripheral blood of Chinese cattle. The PrPC gene was amplified by polymerase chain reaction, using two primers. It was then cloned into pGEM-T Easy Vector. The result of DNA sequencing was indicated that the 795 bp amplified fragment contains the entire PrPC coding sequence, which has no intron and is same
D, Wang   +4 more
openaire   +1 more source

The subcellular trafficking of the prion protein: Characterisation of the function of the PrPc N-terminus

2003
Die transmissiblen spongiformen Enzephalopathien (TSEs) bilden eine Gruppe fataler degenerativer Erkrankungen des zentralen Nervensystems von Mensch und Tier, deren bekannteste Erscheinungsformen die bovine spongiforme Enzephalopathie (BSE) beim Rind, die Traberkrankheit beim Schaf sowie die Creutzfeldt-Jakob-Erkrankung beim Menschen sind.
openaire   +1 more source

Mapping the interactions between prion protein (PrPC) and prion protein fibrils (PrPSc)

Biophysical Journal, 2023
Alyssa M. Thallemer   +2 more
openaire   +1 more source

[Study on the correlation between membrane protein Flotillin-1 and PrPc endocytosis].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2013
To explore whether the membrane-associated protein Flotillin-1 has relationship with endocytosis of PrPc.The expression of Flotillin-1 in different cell lines was detected with the method of Western Blot; the interaction between Flotillin-1 and PrPc in Cells which were treated with copper ions was observed using immunoprecipitation method.(1) Flotillin-
Ke, Ren   +8 more
openaire   +1 more source

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