Results 191 to 200 of about 47,105 (312)

Nadifloxacin: Multimilligram Enantioresolution and Enantioselective Ecotoxicological Studies. [PDF]

open access: yesChirality
Oliveira IE   +9 more
europepmc   +1 more source

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

open access: yesImmunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula   +6 more
wiley   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

open access: yesImmunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang   +9 more
wiley   +1 more source

Innovative Field Applications of Probiotics, Prebiotics, and Medicinal Plant Products for Disease Control in Aquaculture

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz   +5 more
wiley   +1 more source

DrugPred: an EdgeConv-GNN and Bio_ClinicalBERT based polypharmacy ADR prediction and specialist recommendation model. [PDF]

open access: yesFront Artif Intell
Arjay JG   +5 more
europepmc   +1 more source

Immunogenicity and Protective Efficacy of the First Autogenous Aeromonas hydrophila Vaccine for Piaractus brachypomus

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Aeromonas hydrophila is a major zoonotic bacterial pathogen responsible for haemorrhagic septicemia, substantial economic losses in aquaculture and increasing antimicrobial resistance among field isolates. It is also one of the main bacterial species associated with mortality outbreaks in pirapitinga, Piaractus brachypomus, culture in the ...
Layana Aparecida Batista Pereira   +7 more
wiley   +1 more source

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