Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Gastrointestinal adverse events related to monoclonal antibodies: A comprehensive evaluation of data from the FDA Adverse Event Reporting System database. [PDF]
Indian J PharmacolKumar N, Kalaiselvan V, Arora MK.
europepmc +1 more source
maxRgain—An R Package for Maximising Genetic Gains in Polyclonal Selection
Plant Breeding, EarlyView.ABSTRACT Polyclonal selection, which was developed in the context of ancient grapevine varieties, uses intravarietal variability to improve the resilience and sustainability of viticulture. Based on quantitative genetics and linear mixed models, this approach predicts genotypic effects to select a group of clones that, as a whole, satisfy target ...
Sónia Surgy +2 more
wiley +1 more source
Post-marketing safety monitoring of sodium-glucose cotransporter 2 inhibitors for diabetes in cats: a pharmacovigilance study based on the FDA ADAE database. [PDF]
J Vet Intern MedLai X, Chen M, Huang Y, Cheng Y.
europepmc +1 more source
Effects of Atmospheric CO2 Levels on the Susceptibility of Maize to Diverse Pathogens
Plant, Cell &Environment, EarlyView.ABSTRACT Rising atmospheric CO2 has significant implications for crop productivity and food security. Based on studies in C3 plants, elevated CO2 (eCO2) can shape plant‐pathogen interactions, although the outcomes are often variable. The question of how eCO2 influences immunity and disease development in C4 plants, such as the globally important cereal
Ekkachai Khwanbua +5 more
wiley +1 more source
Optimization of brain PET markerless head motion correction in a large human cohort. [PDF]
EJNMMI PhysZeng T +13 more
europepmc +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Microbial volatile organic compounds (mVOCs) enable plants to perceive microbial activity prior to physical contact, yet the contribution of individual bacterial volatiles to immune signalling and disease resistance remains incompletely understood.
Ivan A. Paponov +6 more
wiley +1 more source
Plant immune co-receptors: bridging gaps toward next-generation crop defense. [PDF]
Stress BiolMudasir M, Shahzad A.
europepmc +1 more source
Sugars as Central Integrators of Plant Immunity and Stress Responses
Plant, Cell &Environment, EarlyView.ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło +2 more
wiley +1 more source
Pregnancy-related adverse events and congenital disorders associated with aspirin: A real-world pharmacovigilance analysis of the FDA adverse event reporting system. [PDF]
Medicine (Baltimore)Fang Z, Zhang Y, Xu L, Wang X.
europepmc +1 more source