Tratamento sintomático em cuidados paliativos: Prurido
O prurido é um sintoma que, apesar de aparentemente menos importante, pode afectar bastante a qualidade de vida de alguns doentes terminais. O manejo deste sintoma não se reduz apenas à utilização de anti-histamínicos, pelo que ao longo deste artigo ...
Luísa Carvalho
doaj +2 more sources
PRURIDO E ACHADOS DERMATOLÓGICOS EM PACIENTES EM HEMODIÁLISE
Objetivo: Problemas dermatológicos são freqüentes em pacientes renais crônicos em hemodiálise. Dentre os mais comuns, destaca-se o prurido, que acomete entre 25 e 90% dessa população.
Marcelo Generali da Costa +4 more
doaj +1 more source
Pruritus: still a challenge Prurido: ainda um desafio
Pruritus is a symptom that may be associated with a wide array of diseases - skin diseases, systemic diseases or even those without a defined cause. According to its severity and evolution, it may compromise the patients' quality of life in a significant
Paulo Rowilson Cunha +1 more
doaj +2 more sources
Prurido generalizado na gravidez: a propósito de um caso clínico.
Relata-se o caso clínico de uma grávida que apresenta, em consulta de vigilância da gravidez, prurido generalizado às 35 semanas de gestação. Com base na história clínica e exame físico foram colocadas as seguintes hipóteses de diagnóstico: Colestase ...
Ana Veiga Macedo, Claúdia Marques
doaj +2 more sources
Efficacy and Field Safety of Ilunocitinib for the Control of Allergic Dermatitis in Client-Owned Dogs: A Multicenter, Double-Masked, Randomised, Placebo-Controlled Clinical Trial. [PDF]
Background: Inhibition of the Janus kinase pathway is an established treatment for allergic dermatitis. Objective: To evaluate the efficacy and safety of ilunocitinib for control of pruritus in dogs with allergic dermatitis in a randomised, double‐masked clinical trial.
Forster S +5 more
europepmc +2 more sources
An open-label pilot study on an adsorbent mousse containing adelmidrol in client-owned cats with feline atopic skin syndrome and associated seborrhoea. [PDF]
Background – Besides pruritus and skin lesions, cats with feline atopic skin syndrome (FASS) may have seborrhoea. Hypothesis/Objectives – The aim of this pilot study was to investigate whether an adsorbent mousse containing tapioca starch, adelmidrol and a nonpharmacological antimicrobial complex could decrease FASS‐associated seborrhoea in cats ...
Noli C +4 more
europepmc +2 more sources
Efficacy and field safety of ilunocitinib for the control of atopic dermatitis in client-owned dogs: A multicentre, double-masked, randomised, placebo-controlled clinical trial. [PDF]
Background – Inhibition of the Janus kinase (JAK) pathway is a well‐established option for canine atopic dermatitis (cAD). Objective – To evaluate the efficacy and safety of ilunocitinib, a novel JAK inhibitor for the control of pruritus and skin lesions in client‐owned dogs with cAD.
Forster S +5 more
europepmc +2 more sources
Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. [PDF]
Background – Janus kinase inhibitors (JAKi) have been shown to reduce pruritus and improve associated inflammatory skin lesions in canine atopic dermatitis (cAD). Objective – To evaluate the efficacy and safety of ilunocitinib, in comparison to oclacitinib, for the control of cAD in a randomised, blinded trial.
Forster S +4 more
europepmc +2 more sources
Efficacy of Der f 2/Zen 1-LAMP1 Plasmid-Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof-of-Concept Study. [PDF]
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Bizikova P +6 more
europepmc +2 more sources
Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research. [PDF]
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Tamamoto-Mochizuki C, Mishra SK.
europepmc +2 more sources

