Efficacy and field safety of ilunocitinib for the control of atopic dermatitis in client-owned dogs: A multicentre, double-masked, randomised, placebo-controlled clinical trial. [PDF]
Vet DermatolBackground – Inhibition of the Janus kinase (JAK) pathway is a well‐established option for canine atopic dermatitis (cAD). Objective – To evaluate the efficacy and safety of ilunocitinib, a novel JAK inhibitor for the control of pruritus and skin lesions in client‐owned dogs with cAD.
Forster S +5 more
europepmc +2 more sources
Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. [PDF]
Vet DermatolBackground – Janus kinase inhibitors (JAKi) have been shown to reduce pruritus and improve associated inflammatory skin lesions in canine atopic dermatitis (cAD). Objective – To evaluate the efficacy and safety of ilunocitinib, in comparison to oclacitinib, for the control of cAD in a randomised, blinded trial.
Forster S +4 more
europepmc +2 more sources
Efficacy of Der f 2/Zen 1-LAMP1 Plasmid-Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof-of-Concept Study. [PDF]
Vet DermatolBackground: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Bizikova P +6 more
europepmc +2 more sources
Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research. [PDF]
Vet DermatolBackground – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Tamamoto-Mochizuki C, Mishra SK.
europepmc +2 more sources
Cutaneous epitheliotropic T-cell lymphoma in a sugar glider (Petaurus breviceps). [PDF]
Vet DermatolA 3‐year‐old male sugar glider presented with pruritus and alopecia primarily affecting the back and neck regions. Dermatologic diagnostics ruled out common causes. Skin biopsies revealed cutaneous epitheliotropic T‐cell lymphoma, a rare condition in sugar gliders. Despite treatment, the glider's condition worsened, leading to death.
Amati P +3 more
europepmc +2 more sources
Prurido: da etiopatogénese ao tratamento [PDF]
Revista Medicina Cut�nea Ibero-Latino-Americana, 2021 EnglishItching is a common symptom, affecting up to 38% of the population at some point in life and being a frequent motive of dermatology consultation. Although being multifactorial, many aspects of its pathophysiology continue to be elucidated. Its etiology is variable (hepatic and/or renal diseases, senile pruritus, …), so a complete anamnesis ...
Joana Calvão +2 more
openaire +1 more source
Randomised, Double-Blinded, Placebo-Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions. [PDF]
Vet DermatolABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Sofou EI +4 more
europepmc +2 more sources
Prurido em região frontal da cabeça
Revista de Epidemiologia e Controle de Infecção, 2012 Maiara Costa Beber +1 more
doaj +3 more sources
Effect of Gabapentin Administered With Prednisolone, Ciclosporin or a Placebo on Clinical Outcomes and Motor Activity in Cats With Atopic Skin Syndrome: A Prospective, Blinded, Placebo-Controlled Study. [PDF]
Vet DermatolBackground: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Morency J +10 more
europepmc +2 more sources
Prurido braquiorradial tratado com talidomida [PDF]
Anais Brasileiros de Dermatologia, 2005 Prurido braquiorradial é um tipo de prurido ou sensação de ardor intenso que acomete a região anterior do terço distal dos braços e terço proximal dos antebraços, correspondendo à região do músculo braquiorradial. A doença tem sido associada à radiação solar e também, cogitou-se, a lesões ortopédicas na coluna cervical.
openaire +5 more sources