Results 71 to 80 of about 7,728 (235)
A Rare Case of Prurigo Pigmentosa in Iranian Sibling Couple
Clinical Case ReportsPrurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects the
Saman Al‐Zahawi +4 more
doaj +1 more source
Acta Dermato-Venereologica, 2017 Substance P (SP) and its receptor neurokinin 1 (NK1R) are thought to be involved in the pathogenesis of chronic prurigo. Here, we assessed SP serum levels, cutaneous NK1R expression, and the effects of topical aprepitant, an NK1R antagonist, in patients ...
Tatevik Ohanyan +7 more
doaj +1 more source
Chronic Prurigo: An Unusual Presentation of Hodgkin Lymphoma
Case Reports in Dermatology, 2018 Background: Prurigo nodularis is a condition of unknown origin defined by papulonodular eruption and intense pruritus. Hodgkin lymphoma often presents nonspecific initial symptoms.
Shireen Dumont +2 more
doaj +1 more source
Renal Disease Burden in Prurigo Nodularis: A Systematic Review and Meta‐Analysis
International Journal of Dermatology, EarlyView.
Natalia Chalupczak +3 more
wiley +1 more source
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
International Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
A Case of Linear Exacerbation of Atopic Dermatitis with Secondary Prurigo Nodularis
, 2022 Hyun Jin Kang +4 more
openalex +1 more source
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, Volume 5, Issue 1, Page 171-175, March 2026.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients
The Laryngoscope, Volume 136, Issue 3, Page 1150-1157, March 2026.ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma +7 more
wiley +1 more source
Acta Dermato-Venereologica, 2020 Chronic nodular prurigo presents with multiple pruriginous nodules and severe pruritus. This study aims to explore the treatment course and regimens in patients with chronic nodular prurigo and to analyse predictive factors contributing to therapeutic ...
Sonja Gründel +6 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.ABSTRACT Vixarelimab is a first‐in‐class fully human monoclonal antibody targeting oncostatin M (OSM) receptor beta (OSMRβ). It has been evaluated in Phase 1 and 2 studies in healthy volunteers and patients with chronic pruritic conditions and demonstrated anti‐pruritic efficacy in a Phase 2 study in prurigo nodularis, but detailed pharmacokinetic ...
Fei Tang +6 more
wiley +1 more source