Results 141 to 150 of about 6,645 (195)

Efficacy and Safety of Nemolizumab in Patients With Prurigo Nodularis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Cureus
This meta-analysis evaluated the efficacy and safety of nemolizumab in treating prurigo nodularis through a systematic review of randomized controlled trials.
Kunal Sinha, Tanya Sinha, Neeharika Muppa, Nabeela Kanwal, Keron Blair, Sandipkumar S Chaudhari, Calvin R Wei, Adil Amin   +7 more
semanticscholar   +1 more source

Taiwanese Dermatological Association consensus for the diagnosis and management of prurigo nodularis

Zhōnghuá Pífūkē Yīxué Zázhì
Prurigo nodularis (PN) is a chronic neuroinflammatory skin disease that, while considered rare, is likely underestimated. Due to its complex presentation, misdiagnosis is not uncommon, highlighting the need for greater awareness among healthcare ...
Cheng-Che E Lan, Wen-Hung Chung, Yang-Yi Chen, P. Hsiao, Yu-Ping Hsiao, Chih-Hung Lee, Tzu-Kai Lin, Hsing-San Yang   +7 more
semanticscholar   +1 more source

Dermoscopy of prurigo nodularis

The Journal of Dermatology, 2015
AbstractThe diagnosis of prurigo nodularis is mainly clinical, based on its distinctive features. However, in some cases it may be difficult to differentiate it from other nodular dermatoses only on the clinical basis, thus requiring histopathological examination to reach a definitive diagnosis.
Errichetti, E., Piccirillo, A., STINCO, Giuseppe   +2 more
openaire   +2 more sources

Therapeutic Outcomes Across JAK Inhibitors in Prurigo Nodularis.

Clincal and Experimental Dermatology
BACKGROUND Prurigo nodularis (PN) is a debilitating skin condition. When inadequate disease control is achieved or other systemic therapies are contraindicated, JAK inhibitors may be considered although real-world evidence remains limited. OBJECTIVE To
G. Avallone, Andrea Bombelli, L. Valtellini, G. Tavoletti, Benedetta Galli, Mariateresa Rossi, M. Maurelli, G. Girolomoni, L. Gargiulo, A. Narcisi, Francesca di Vico, M. Napolitano, Laura Lazzeri, L. Calabrese, S. Caccavale, A. Balato, F. Barei, P. Calzari, Caterina Foti, I. Trave, E. Cozzani, F. Rongioletti, Sveva Lenti, Carlotta Gurioli, Eustachio Nettis, F. Caroppo, E. Errichetti, L. Bonzano, N. Gori, K. Peris, S. Lembo, L. Del Regno, M. Esposito, M. Fargnoli, Paola Savoia, Elia Esposto, R. Giuffrida, Fabrizio Guarneri, C. Patruno, E. Pezzolo, L. Stingeni, K. Hansel, L. Mastorino, M. Ortoncelli, Simone Ribero, A. Marzano, S. Ferrucci   +46 more
semanticscholar   +1 more source

Prurigo nodularis: A review

Australasian Journal of Dermatology, 2005
SUMMARYPrurigo nodularis is a chronic condition characterized by a papulonodular pruriginous eruption of unknown aetiology. This condition is a difficult disease to treat and causes frustration to both the patient and the treating doctor. A variety of systemic conditions have been reported to be associated with prurigo nodularis. The mechanism by which
Michael R, Lee, Stephen, Shumack
openaire   +2 more sources

Efficacy and Safety of Nemolizumab in Patients With Moderate to Severe Prurigo Nodularis: The OLYMPIA 1 Randomized Clinical Phase 3 Trial.

JAMA dermatology
Importance Prurigo nodularis (PN) is a chronic and debilitating skin condition, characterized by intense itch with multiple nodular lesions. Nemolizumab demonstrated significant improvements in itch and skin nodules in adults with moderate to severe PN ...
Sonja Ständer, Gil Yosipovitch, F. Legat, Adam Reich, Carle Paul, Dagmar Simon, L. Naldi, Martin Metz, Athanasios Tsianakas, Andrew E. Pink, Simon Fage, G. Micali, E. Weisshaar, Hema Sundaram, Andrei Metelitsa, Matthias Augustin, Andreas Wollenberg, Bernhard Homey, M. Fargnoli, H. Sofen, Neil J Korman, L. Skov, Xiaoxiao Chen, Zarif K. Jabbar-Lopez, C. Piketty, S. Kwatra   +25 more
semanticscholar   +1 more source

Prurigo nodularis.

The Journal of family practice, 1993
Prurigo nodularis is a chronic skin disorder that is frequently misdiagnosed. It is characterized by multiple pea-sized nodules that develop on the skin, particularly on the anterior leg and thigh. These lesions are intensely pruritic and frequently become excoriated and infected.
P W, Linhardt, A D, Walling
openaire   +1 more source

The epidemiology of prurigo nodularis in Belgium.

EJD. European journal of dermatology
Prurigo nodularis (PN) is a rare, severely pruritic chronic skin disease, which seriously reduces patients' quality of life. PN prevalence in Belgium is unknown.
Ellen Van Den Steen, V. Reynaert, Annelien Jadoul, Martine Grosber, Diederik DE Cock, Jan Gutermuth   +5 more
semanticscholar   +1 more source

Epigenetic Profiling Reveals Neuroimmune and Fibrotic Pathway Dysregulation in Prurigo Nodularis.

British Journal of Dermatology
This study integrates genome-wide DNA methylation and transcriptomic profiling to reveal key dysregulated pathways in prurigo nodularis (PN). Lesional PN skin exhibits distinct epigenetic reprogramming that activates neuroimmune, fibrotic, and ...
Shahin Shahsavari, K. Vats, Jonathan Wang, S. Shahsavari, Meena Alzamani, Jaya Manjunath, Ze Zhang, Mariam Sobh, L.J. Born, Bradley Anderson, S.M. Yossef, Y. Akiska, Davies Gage, M.M. Kwatra, S. Kwatra   +14 more
semanticscholar   +1 more source

Prurigo nodularis and associated dermatological conditions in Finland from 1995 to 2022.

British Journal of Dermatology
This registry based study analysed the epidemiology of prurigo nodularis in Finland in 1995-2022.Surprisingly, only a fifth of Finnish patients with prurigo nodularis had preceding dermatological diagnosis.
L. Huilaja, J. Jokelainen, S. Sinikumpu
semanticscholar   +1 more source