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Comorbidities in prurigo nodularis
Clinics in DermatologyPrurigo nodularis (PN) is a chronic inflammatory skin condition characterized by intense pruritus and hyperkeratotic nodules commonly found on the trunk and extremities. The pathogenesis of PN involves neuroimmune dysregulation, mediated by various inflammatory cytokines and neuropeptides. PN significantly impacts patients' quality of life.
Jaya, Manjunath +3 more
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Prurigo nodularis and the microbiome
Clinics in DermatologyPrurigo nodularis (PN) is a chronic skin condition that profoundly impacts quality of life. Histopathological studies of itchy hyperkeratotic nodules show dense infiltrates of T lymphocytes, mast cells, and eosinophils. A robust inflammatory response is implicated, coupled with key changes in neuronal plasticity that affect nerve fiber architecture and
Hyun Ji, Lee, Hei Sung, Kim
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Southern Medical Journal, 1975
Patients with uremia frequently have generalized pruritus that is usually related to a disturbance of calcium and phosphorus metabolism. This report describes three patients with uremia who had prurigo nodularis due to localized scratching and rubbing. The diagnosis of uremia in one case was made when the patient was hospitalized for evaluation of skin
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Patients with uremia frequently have generalized pruritus that is usually related to a disturbance of calcium and phosphorus metabolism. This report describes three patients with uremia who had prurigo nodularis due to localized scratching and rubbing. The diagnosis of uremia in one case was made when the patient was hospitalized for evaluation of skin
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Bullous pemphigoid and prurigo nodularis
Journal of the American Academy of Dermatology, 1986Bullous pemphigoid is a chronic blistering disorder characterized by specific clinical, histologic, and immunofluorescent findings. Several variants have been described, including pemphigoid nodularis, which may mimic or evolve from or into prurigo nodularis. The casual relationship between prurigo nodularis and bullous pemphigoid is unknown.
R K, Roenigk, M V, Dahl
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Alitretinoin for prurigo nodularis
Clinical and Experimental Dermatology, 2020T, Maqbool, J N, Kraft
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The Journal of family practice, 1993
Prurigo nodularis is a chronic skin disorder that is frequently misdiagnosed. It is characterized by multiple pea-sized nodules that develop on the skin, particularly on the anterior leg and thigh. These lesions are intensely pruritic and frequently become excoriated and infected.
P W, Linhardt, A D, Walling
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Prurigo nodularis is a chronic skin disorder that is frequently misdiagnosed. It is characterized by multiple pea-sized nodules that develop on the skin, particularly on the anterior leg and thigh. These lesions are intensely pruritic and frequently become excoriated and infected.
P W, Linhardt, A D, Walling
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Treatment of prurigo nodularis with pregabalin.
Journal of clinical pharmacy and therapeutics, 2012Prurigo nodularis (PN) is a chronic skin condition that is difficult to treat. Pregabalin is one of the possible treatments for PN but its safety and efficacy are not well defined. We aimed to assess the efficacy of pregabalin in patients with PN.Thirty patients (10 men, 20 women; mean age 51.6 ± 9.39 years) were treated with pregabalin (75 mg/day) for
Mazza, Marianna +5 more
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Neurohistological Changes in Prurigo Nodularis
Archives of Dermatology, 1964The innervation of a nodule from a patient with prurigo nodularis was studied using the improved silver impregnation technique of Richardson (1960). Profound changes were seen in nerve fibers, where there was a very marked acceleration in the rate of "turnover," and in Schwann cells, where there was hyperplasia and schwannoma formation.
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Helicobacter pylori and prurigo nodularis.
Hepato-gastroenterology, 1999Numerous data have suggested that there may be a relationship between Helicobacter pylori (H. pylori) infection and extragastric diseases, including dermatological pathologies. We studied some cases of Hide's Prurigo Nodularis (NP), a very itchy skin disease of unknown origin, in order to asses whether there is a pathogenic correlation between PN and H.
NERI, Sergio +4 more
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